<?xml version="1.0" encoding="UTF-8"?><rss xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:atom="http://www.w3.org/2005/Atom" version="2.0" xmlns:itunes="http://www.itunes.com/dtds/podcast-1.0.dtd" xmlns:googleplay="http://www.google.com/schemas/play-podcasts/1.0"><channel><title><![CDATA[Never Delegate Understanding: Health & Veritas]]></title><description><![CDATA[Harlan Krumholz and  Howard Forman, two Yale physician-professors, discuss the latest news and ideas in healthcare and seek out the truth amid the noise.

Health & Veritas is produced with the Yale School of Management and the Yale School of Public Health. 

New episodes are available every Thursday. ]]></description><link>https://neverdelegateunderstanding.substack.com/s/health-and-veritas</link><image><url>https://substackcdn.com/image/fetch/$s_!5i8G!,w_256,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F6338c6de-5a88-4641-ad5c-c7ef74997334_1280x1280.png</url><title>Never Delegate Understanding: Health &amp; Veritas</title><link>https://neverdelegateunderstanding.substack.com/s/health-and-veritas</link></image><generator>Substack</generator><lastBuildDate>Thu, 13 Aug 2026 23:32:01 GMT</lastBuildDate><atom:link href="https://neverdelegateunderstanding.substack.com/feed" rel="self" type="application/rss+xml"/><copyright><![CDATA[Harlan Krumholz]]></copyright><language><![CDATA[en]]></language><webMaster><![CDATA[neverdelegateunderstanding@substack.com]]></webMaster><itunes:owner><itunes:email><![CDATA[neverdelegateunderstanding@substack.com]]></itunes:email><itunes:name><![CDATA[Harlan Krumholz]]></itunes:name></itunes:owner><itunes:author><![CDATA[Harlan Krumholz]]></itunes:author><googleplay:owner><![CDATA[neverdelegateunderstanding@substack.com]]></googleplay:owner><googleplay:email><![CDATA[neverdelegateunderstanding@substack.com]]></googleplay:email><googleplay:author><![CDATA[Harlan Krumholz]]></googleplay:author><itunes:block><![CDATA[Yes]]></itunes:block><item><title><![CDATA[Science, Politics, and Personality]]></title><description><![CDATA[Howie and Harlan discuss Dr. Vinay Prasad&#8217;s departure from the FDA after a backlash against his decisions on Sarepta&#8217;s Duchenne muscular dystrophy gene therapy. Also examined: AI in clinical settings, changes in NIH grantmaking, and the 60th...]]></description><link>https://neverdelegateunderstanding.substack.com/p/science-politics-and-personality-cd6</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/science-politics-and-personality-cd6</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 31 Jul 2025 13:48:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298511/c7ff3fc0deef15a7aa43249d8d1a3852.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan discuss Dr. Vinay Prasad&#8217;s departure from the FDA after a backlash against his decisions on Sarepta&#8217;s Duchenne muscular dystrophy gene therapy. Also examined: AI in clinical settings, changes in NIH grantmaking, and the 60th anniversary of Medicare and Medicaid.</p><p>Links:</p><p>Sarepta and the FDA</p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.statnews.com%2F2025%2F07%2F30%2Fsarepta-therapeutics-elevidys-video-explainer-status-report-episode-8%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457569301%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=PvihBwwrLuDxdfXbF5SLM8uqUp123wp%2BrAUG22x81G4%3D&amp;reserved=0">&#8220;STAT breaks down the confusing, heartbreaking Sarepta saga&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.statnews.com%2F2025%2F07%2F22%2Ffda-sarepta-elevidys-muscular-dystrophy-drug%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457579194%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=TtSlrDYWaw4wbvnJx9hNBNhEZfOkTEW2pEjPf5rQTjE%3D&amp;reserved=0">&#8220;Sarepta Therapeutics&#8217; Duchenne therapy faces &#8216;arduous&#8217; path back to market, senior FDA official says&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.statnews.com%2F2025%2F07%2F24%2Fduchenne-muscular-dystrophy-families-sarepta-elevydis%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457588760%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=QlnnTZIGQVqTRtkRvbGdFpRDhz96bh7GGVzLN6t%2BAiw%3D&amp;reserved=0">&#8220;For many Duchenne families, halt to gene therapy is heartbreak upon heartbreak&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.fiercepharma.com%2Fpharma%2Ffda-launches-probe-new-elevidys-death-sarepta-roche-stress-gene-therapy-not-fault&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457601491%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=xUnGqJpi1PME1yzcXyRoQTABJh%2BQCBiNxyss7vH2Z8E%3D&amp;reserved=0">&#8220;FDA launches probe into new Elevidys death as Sarepta, Roche stress gene therapy not at fault&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.fda.gov%2Fnews-events%2Fpress-announcements%2Ffda-recommends-removal-voluntary-hold-elevidys-ambulatory-patients&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457612090%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=crZh%2BYW%2FQu8GvcZaKX1XmajR4Nkk%2BtBNGeAwPbFPLZs%3D&amp;reserved=0">&#8220;FDA Recommends Removal of Voluntary Hold for Elevidys for Ambulatory Patients&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.fiercepharma.com%2Fpharma%2Ffda-takes-u-turn-sareptas-elevidys-backing-duchenne-gene-therapy-again-ambulatory-patients&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457622072%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=nGRB%2FrwTJWQFrNDUwXZzxZX4kvJFFIdDE%2FjeHMoY7No%3D&amp;reserved=0">&#8220;FDA takes U-turn on Sarepta&#8217;s Elevidys, backing Duchenne gene therapy again in ambulatory patients&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.cnn.com%2F2025%2F07%2F29%2Fhealth%2Fvinay-prasad-fda&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457631846%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=5n%2FHE5NQ%2BoagxlPa3my88gxhuXt1SdfMCRq3UNr5O1Y%3D&amp;reserved=0">&#8220;Controversial FDA official Dr. Vinay Prasad departs agency&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nytimes.com%2F2025%2F03%2F28%2Fhealth%2Ffda-vaccines-rfk-jr-peter-marks.html&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457641892%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=f%2FbxSA%2FGC7IgS5Nwawt82D4gwmxhGfRZjrmCXHnSwOg%3D&amp;reserved=0">&#8220;Top F.D.A. Vaccine Official Resigns, Citing Kennedy&#8217;s &#8216;Misinformation and Lies&#8217;&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.wsj.com%2Fopinion%2Fvinay-prasad-is-a-bernie-sanders-acolyte-in-maha-drag-healthcare-bfc3be57%3Fgaa_at%3Deafs%26gaa_n%3DASWzDAh5e36k14t3ZSdLLjU1EzLOtYHerQCiqLaakklsI-2-a-CTmFd-d0MEll0zTYw%253D%26gaa_ts%3D688a5695%26gaa_sig%3DY_ajR2KFqNWk5LUydraHPEk2AlMUMvo--4jbPF3d4LL2G-kYcOh-CrD-MWXvLHiYGVr99CmboQS29-DFrEE2dg%253D%253D&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457651490%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=HFAcUhG2DPdjrQkKZAcLhQtviS7bgiHAXjW3yB3xdpU%3D&amp;reserved=0">&#8220;Vinay Prasad Is a Bernie Sanders Acolyte in MAHA Drag&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.npr.org%2F2007%2F11%2F10%2F5470430%2Ftimeline-the-rise-and-fall-of-vioxx&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457661112%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=dPLC5Q3P8WKGENP%2Beku4yTqrz6ffwB2kXO%2B1OI5G3NA%3D&amp;reserved=0">&#8220;Timeline: The Rise and Fall of Vioxx&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpmc.ncbi.nlm.nih.gov%2Farticles%2FPMC1779871%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457670731%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=6TC3Ju1h6ducNGNsguvCaPEhCZn2TgIVFMN0IrpsdII%3D&amp;reserved=0">&#8220;What have we learnt from Vioxx?&#8221;</a></p><p>THC in pizza dough</p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nytimes.com%2F2025%2F07%2F28%2Fwell%2Fwisconsin-restaurant-thc-poisoning.html&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457680469%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=e6W2l7LB%2BKhqPy8A1012tD2VOTsMyNKhuA8gSBSYL64%3D&amp;reserved=0">&#8220;C.D.C. Ties 85 Cases of THC-Related Symptoms to Wisconsin Restaurant&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.cdc.gov%2Fmmwr%2Fvolumes%2F74%2Fwr%2Fmm7427a2.htm&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457690599%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=HgQv%2FEDi%2FvOOzQjkyHEfYTzcIdoZ1KTmOCpIgrf64bs%3D&amp;reserved=0">&#8220;Tetrahydrocannabinol Intoxication from Food at a Restaurant &#8212; Wisconsin, October 2024&#8221;</a></p><p>NIH funding</p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.statnews.com%2F2025%2F07%2F29%2Fnih-cancer-institute-shrink-number-of-funded-research-grants%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457700475%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=DkahOV6kVv0i2Eg6uX3HVKYq2XPYfd6vrtpwZoS9zGM%3D&amp;reserved=0">&#8220;NIH is shrinking the number of research projects it funds due to a new Trump policy&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgrants.nih.gov%2Fgrants%2Fguide%2Fnotice-files%2FNOT-OD-25-132.html&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457710259%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=VyBCyMmB9R%2BDj74YJKoxIq%2FxyR5DPc8RlthfBEsB3aU%3D&amp;reserved=0">NIH: Supporting Fairness and Originality in NIH Research Applications</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.science.org%2Fcontent%2Farticle%2Ffearful-ai-generated-grant-proposals-nih-limits-scientists-six-applications-year&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457719980%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=rXuXs13HSIzGEBoSXSdJLIV06RtiZ1QBlJrOcOTKbwM%3D&amp;reserved=0">&#8220;Fearful of AI-generated grant proposals, NIH limits scientists to six applications per year&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.statnews.com%2F2025%2F04%2F16%2Ftrump-draft-budget-proposes-nih-consolidation-40-percent-cut%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457730084%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=IuyI57Nrl4rVbZiJEMwLXPHEjGK8wEyt322U1raTzJc%3D&amp;reserved=0">&#8220;Trump budget draft proposes NIH consolidation and 40% spending cut&#8221;</a></p><p>Raw milk</p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.cdc.gov%2Fmmwr%2Fvolumes%2F74%2Fwr%2Fmm7427a1.htm&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457739791%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=MkS8F20xLUaw21bCvoZaV6zWEYkZL7215t0a8TP6IKs%3D&amp;reserved=0">&#8220;Outbreak of Salmonella Typhimurium Infections Linked to Commercially Distributed Raw Milk &#8212; California and Four Other States, September 2023&#8211;March 2024&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.fda.gov%2Ffood%2Fbuy-store-serve-safe-food%2Fdangers-raw-milk-unpasteurized-milk-can-pose-serious-health-risk%23%3A~%3Atext%3DRaw%2520milk%2520is%2520milk%2520from%2Coften%2520called%2520%25E2%2580%259Cfood%2520poisoning.%25E2%2580%259D&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457753303%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=J7Isyl4i1xUtfm6aaAsLjuvVv16qfQveL15%2B%2Fjsq%2BEg%3D&amp;reserved=0">&#8220;The Dangers of Raw Milk: Unpasteurized Milk Can Pose a Serious Health Risk&#8221;</a></p><p>AI in healthcare update</p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.ambiencehealthcare.com%2Fblog%2Fambience-healthcare-announces-243-million-series-c-to-scale-its-ai-platform-for-health-systems&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457764527%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=Hk0nIFrGWOhnkhpe58DfkiZZ3uowmmg5%2F4%2BVWvpfIXw%3D&amp;reserved=0">&#8220;Ambience Healthcare Announces $243 Million Series C to Scale its AI Platform for Health Systems&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.statnews.com%2F2025%2F07%2F24%2Fdoximity-enters-crowded-ai-scribe-market-with-free-offering%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457775232%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=B6QXAhv1iDkaBvdMu5FnhAO%2B3FJfK3TGoUNo6olGnlk%3D&amp;reserved=0">&#8220;As ambient scribes face off, Doximity lures doctors with a free option&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.aidoc.com%2Fsolutions%2Fradiology%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457785782%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=t0H0HNSducFjQM6lT5jHs0Vr9ShjwACczga2Njf6rHI%3D&amp;reserved=0">Aidoc: &#8220;AI Empowering Radiologists&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F36736547%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457795680%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=dRSoJS8q4TuAWVzo7Fapx%2BzPQ3lQEJvR8z%2BmZTOEM3o%3D&amp;reserved=0">&#8220;Clinical Implementation of a Combined Artificial Intelligence and Natural Language Processing Quality Assurance Program for Pulmonary Nodule Detection in the Emergency Department Setting&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpubs.rsna.org%2Fdoi%2Ffull%2F10.1148%2Fradiol.240844&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457805768%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=bwJ1xLiGK0h5uRANPfH0mUexAzFd4oJyFJouv0f0aX4%3D&amp;reserved=0">&#8220;Large Language Models as an Inexpensive and Effective Extra Set of Eyes in Radiology Reporting&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F39721866%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457815974%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=X4KDRwB9KJ66ekcqKiT%2FgJR8HdWXpATkmktbZk4aCKg%3D&amp;reserved=0">&#8220;Current Trends in Remote and Flexible Work Options in Radiology and Perception of Impact on Radiologist Well-being&#8221;</a></p><p>Medicare and Medicaid 60th anniversary</p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.cms.gov%2Fabout-cms%2Fwho-we-are%2Fhistory&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457826142%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=A54BUUUECaAGupROvrVvbqWdwiCWyGfM5mi4G59Q%2Flo%3D&amp;reserved=0">CMS&#8217; program history</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.theguardian.com%2Fus-news%2F2025%2Fjul%2F30%2Fmedicaid-medicare-cuts-trump-republicans-history&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457836588%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=AnAiLSnD2DvBo4YTPR4z1oaKEVquUB5ym9eDY47uZxU%3D&amp;reserved=0">&#8220;Medicare and Medicaid turn 60 &#8211; and face historic cuts decades in the making&#8221;</a></p><p>UnitedHealth and Medicare Advantage</p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.cnbc.com%2F2025%2F07%2F29%2Funitedhealth-group-unh-earnings-report-q2-2025.html&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457846678%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=70vKPb2aEw2vMw6VBE2%2BjqGkOiwBdEPGHZdrxKYZb9g%3D&amp;reserved=0">&#8220;UnitedHealth says 2025 earnings will be worse than expected as high medical costs dog insurers&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.fiercehealthcare.com%2Fpayers%2Funitedhealth-cuts-2025-outlook-elevated-medical-costs-continue-sting&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457856686%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=E6KB8LXMxv9ETU3s9qm50cefdu2Pj9%2Bme%2BUhD3%2BXilA%3D&amp;reserved=0">&#8220;UnitedHealthcare to exit certain Medicare Advantage markets as costs balloon, impacting 600K enrollees&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.reuters.com%2Fbusiness%2Fhealthcare-pharmaceuticals%2Fnovo-nordisk-slides-further-us-competition-new-ceo-concerns-2025-07-30%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457866875%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=rRBU2x7zwRPB%2B1FRT4rfk37Gy7gcJNHCPytWaUSO%2FZg%3D&amp;reserved=0">&#8220;Novo Nordisk slides further on US competition, new CEO concerns&#8221;</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.thebulwark.com%2Fp%2Fdemocrats-must-fix-medicaid-not-just-undo-trump-bbb-damage-universal-coverage-seven-principles-reform-health-care&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7C30884aa4bdbe432c578d08ddcfa91e2f%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638895047457876622%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=9NwJYVJLpyej1gG2Phvno8fniLjEp%2Fjau%2Fwez5qfTeE%3D&amp;reserved=0">&#8220;Dems Must Really Fix Medicaid, Not Just Undo Trump&#8217;s Damage to It&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Katelyn Jetelina: A Visit from Your Local Epidemiologist]]></title><description><![CDATA[Howie and Harlan are joined by public health communicator Katelyn Jetelina for updates on COVID-19 and other issues, and to discuss how her emails to students and colleagues in the early days of the pandemic turned into a platform with global reach....]]></description><link>https://neverdelegateunderstanding.substack.com/p/katelyn-jetelina-a-visit-from-your-919</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/katelyn-jetelina-a-visit-from-your-919</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 24 Jul 2025 13:25:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298512/69485e5147eabd60b5eb328acc759243.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by public health communicator Katelyn Jetelina for updates on COVID-19 and other issues, and to discuss how her emails to students and colleagues in the early days of the pandemic turned into a platform with global reach. Harlan looks at how AI is being used on both sides of the battle between providers and insurers over claims; Howie reports on a setback with a promising gene therapy for Duchenne muscular dystrophy.</p><p>Links:</p><p>Insurance Claims, AI, and Wearables</p><p><a href="https://www.elevancehealth.com/newsroom/elv-quarterly-earnings-q2-2025">&#8220;Elevance Health Reports Second Quarter 2025 Results&#8221;</a></p><p><a href="https://www.statnews.com/2025/07/17/elevance-fourth-us-health-insurer-to-lower-or-scrap-forecasts/">&#8220;Elevance lowers profit outlook, warns things will get worse for health insurers &#8220;</a><a href="https://www.fiercehealthcare.com/payers/blue-kc-wrongfully-denied-medical-diagnoses-hospital-alleges-ai-driven-claims-lawsuit">&#8220;Blue KC wrongfully denied medical diagnoses, hospital alleges in AI-driven claims lawsuit&#8221;</a></p><p><a href="https://www.fiercehealthcare.com/payers/oscar-health-cuts-full-year-guidance-estimates-2025-loss-aca-marketplace-stumbles">&#8220;Oscar Health cuts full-year guidance, estimates 2025 loss as ACA marketplace stumbles&#8221;</a></p><p><a href="https://www.whoop.com/us/en/?srsltid=AfmBOopT0vyyowMPeZrACJHHB-u4YkyJl5zerArncQLa7eeigURpMqeq">Whoop</a></p><p><a href="https://www.whoop.com/us/en/thelocker/blood-pressure-insights/?srsltid=AfmBOor05a-YgUCf1F0gYhYjViICWk1uRTPg7bydNu-FWqhltjWmgyEO">&#8220;WHOOP Delivers Innovative Blood Pressure Insights for a Deeper Look at Your Well-Being&#8221;</a></p><p><a href="https://www.whoop.com/de/en/thelocker/heart-screener/">&#8220;Introducing Heart Screener: A smarter way to stay connected to your heart health&#8221;</a></p><p><a href="https://www.cnbc.com/2025/07/15/whoop-fda-blood-pressure-feature-wearables.html">&#8220;Whoop says FDA is &#8216;overstepping its authority&#8217; with warning about blood pressure feature&#8221;</a></p><p><a href="https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/whoop-inc-709755-07142025">FDA: WARNING LETTER, WHOOP, Inc.</a></p><p><a href="https://abcnews.go.com/Health/rfk-jr-wearables-benefits-risks/story?id=123422287">&#8220;RFK Jr. wants everyone to use wearables. What are the benefits, risks?&#8221;</a></p><p><a href="https://time.com/6555701/apple-remove-blood-oxygen-tool-watches/">&#8220;Apple to Sell Watches With Blood-Oxygen Feature Disabled After Legal Setback&#8221;</a></p><p>Your Local Epidemiologist</p><p><a href="https://yourlocalepidemiologist.substack.com/">Your Local Epidemiologist</a></p><p><a href="https://www.kff.org/health-information-trust/press-release/poll-trust-in-public-health-agencies-and-vaccines-falls-amid-republican-skepticism/">&#8220;Poll: Trust in Public Health Agencies and Vaccines Falls Amid Republican Skepticism&#8221;</a></p><p><a href="https://ysph.yale.edu/news-article/popular-epidemiologist-lays-out-future-path-of-public-health-communication/">&#8220;Popular epidemiologist lays out future path of public health communication&#8221;</a></p><p><a href="https://www.pophive.org/">Yale School of Public Health: PopHIVE</a></p><p><a href="https://yourlocalepidemiologist.substack.com/p/nih-the-quiet-engine-of-science-is">Katelyn Jetelina: &#8220;NIH: The quiet engine of science is being dismantled&#8221;</a></p><p><a href="https://yourlocalepidemiologist.substack.com/p/covid-19-in-pockets-sugar-cane-isnt">Katelyn Jetelina: &#8220;Covid-19 in pockets, sugar cane isn't better, ticks march on, rescission cuts (vs. everything else), bright spots, and more&#8221;</a></p><p><a href="https://www.mayoclinic.org/diseases-conditions/norovirus/symptoms-causes/syc-20355296">Mayo Clinic: Norovirus infection</a></p><p><a href="https://yourlocalepidemiologist.substack.com/p/the-show-must-go-on">Katelyn Jetelina: &#8220;The show must go on...&#8221;</a></p><p><a href="https://yourlocalepidemiologist.substack.com/p/harassment-against-scientists-is?utm_source=publication-search">Katelyn Jetelina: &#8220;Harassment against scientists is out of control&#8221;</a></p><p><a href="https://yourlocalepidemiologist.substack.com/p/medicaid-cuts-the-how-and-why">Katelyn Jetelina: &#8220;Medicaid cuts: The how and why&#8221;</a></p><p><a href="https://www.cdc.gov/bird-flu/situation-summary/index.html">CDC: H5 Bird Flu: Current Situation</a></p><p><a href="https://www.cdc.gov/cfa-modeling-and-forecasting/rt-estimates/index.html">CDC: Current Epidemic Trends (Based on Rt) for States&#8221;</a></p><p><a href="https://www.cdc.gov/measles/data-research/index.html">CDC: Measles Cases and Outbreaks</a></p><p>Treating Duchenne Muscular Dystrophy</p><p><a href="https://my.clevelandclinic.org/health/diseases/23538-duchenne-muscular-dystrophy-dmd">Cleveland Clinic: Duchenne Muscular Dystrophy (DMD)</a></p><p><a href="https://www.statnews.com/2024/06/20/fda-sarepta-gene-therapy-elevidys-duchenne-muscular-dystrophy/#:~:text=The%20Food%20and%20Drug,authorization%20handed%20down%20last%20year">&#8220;FDA approves Sarepta&#8217;s Duchenne gene therapy for nearly all patients&#8221;</a></p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC11750718/">&#8220;AAV gene therapy for Duchenne muscular dystrophy: the EMBARK phase 3 randomized trial&#8221;</a></p><p><a href="https://www.statnews.com/2025/07/18/sarepta-gene-therapy-muscular-dystrophy-limb-girdle-patient-death/">&#8220;Patient dies in Sarepta gene therapy trial, adding to safety concerns&#8221;</a></p><p><a href="https://www.fda.gov/news-events/press-announcements/fda-requests-sarepta-therapeutics-suspend-distribution-elevidys-and-places-clinical-trials-hold">&#8220;FDA Requests Sarepta Therapeutics Suspend Distribution of Elevidys and Places Clinical Trials on Hold for Multiple Gene Therapy Products Following 3 Deaths&#8221;</a></p><p><a href="https://www.statnews.com/2025/07/21/sarepta-will-stop-shipping-elevidys-fda-duchenne-muscular-dystrophy/">&#8220;In surprise reversal, Sarepta Therapeutics says it will pause shipments of Duchenne gene therapy&#8221;</a></p><p><a href="https://www.biopharmadive.com/news/sarepta-layoffs-restructuring-elevidys-duchenne-research-cuts/753256/">&#8220;Sarepta to lay off about 500 employees after Duchenne gene therapy setbacks&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Seth Berkowitz: The Power Problem]]></title><description><![CDATA[Howie and Harlan are joined by Seth Berkowitz, an internist and health equity expert, who argues that we know how to keep people healthier but are lacking the political will and commitment to do so. Harlan reports on a rapidly growing AI platform for...]]></description><link>https://neverdelegateunderstanding.substack.com/p/seth-berkowitz-the-power-problem-cd0</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/seth-berkowitz-the-power-problem-cd0</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 17 Jul 2025 13:35:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298513/ca5248740f83578fa02c4d6c95d483fd.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by Seth Berkowitz, an internist and health equity expert, who argues that we know how to keep people healthier but are lacking the political will and commitment to do so. Harlan reports on a rapidly growing AI platform for doctors; Howie explains why the budget bill could reduce access to medical school.&nbsp;</p><p>Links:</p><p>OpenEvidence</p><p><a href="https://www.openevidence.com/">OpenEvidence</a></p><p><a href="https://www.prnewswire.com/news-releases/openevidence-the-fastest-growing-application-for-physicians-in-history-announces-210-million-round-at-3-5-billion-valuation-302505806.html">&#8220;OpenEvidence, the Fastest-Growing Application for Physicians in History, Announces $210 Million Round at $3.5 Billion Valuation&#8221;</a></p><p><a href="https://www.forbes.com/sites/amyfeldman/2025/07/15/this-ai-founder-became-a-billionaire-by-building-chatgpt-for-doctors/">&#8220;This AI Founder Became A Billionaire By Building ChatGPT For Doctors&#8221;</a></p><p><a href="https://www.forbes.com/sites/antoinegara/2018/03/06/wall-street-tech-spree-with-kensho-acquisition-sp-global-makes-largest-a-i-deal-in-history/">&#8220;Wall Street Tech Spree: With Kensho Acquisition S&amp;P Global Makes Largest A.I. Deal In History&#8221;</a></p><p><a href="https://www.forbes.com/profile/daniel-nadler/">Forbes Profile: Daniel Nadler</a></p><p><a href="https://ai.clinicalkey.com/">ClinicalKey AI</a></p><p>Seth Berkowitz</p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/sarah-taylor-the-science-of-breastfeeding">Health &amp; Veritas Ep. 164: Sarah Taylor: The Science of Breastfeeding</a></p><p><a href="https://www.ncdhhs.gov/about/department-initiatives/healthy-opportunities/healthy-opportunities-pilots">North Carolina Department of Health and Human Services: Healthy Opportunities Pilots</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/40014313/">Seth Berkowitz: &#8220;Medicaid Spending and Health-Related Social Needs in the North Carolina Healthy Opportunities Pilots Program&#8221;</a></p><p><a href="https://news.unchealthcare.org/2025/03/nc-healthy-opportunities-program-helped-reduce-medicaid-costs/">&#8220;NC Healthy Opportunities Program Helped Reduce Medicaid Costs&#8221;</a></p><p><a href="https://www.press.jhu.edu/books/title/12917/equal-care?srsltid=AfmBOoprDl0-0fcGbNeet2P0xqY6e7uV3f0ZYNPHlIgGhjVc_XvmDURK">Seth Berkowitz: </a><em><a href="https://www.press.jhu.edu/books/title/12917/equal-care?srsltid=AfmBOoprDl0-0fcGbNeet2P0xqY6e7uV3f0ZYNPHlIgGhjVc_XvmDURK">Equal Care: Health Equity, Social Democracy, and the Egalitarian State</a></em></p><p><a href="https://www.ers.usda.gov/topics/food-nutrition-assistance/food-security-in-the-us/key-statistics-graphics">USDA: Food Security in the U.S.</a></p><p><a href="https://www.nytimes.com/interactive/2025/03/07/us/trump-federal-agencies-websites-words-dei.html">&#8220;These Words Are Disappearing in the New Trump Administration&#8221;</a></p><p><a href="https://www.statnews.com/2025/03/10/google-health-equity-removed-from-website-trump-dei-attacks/">&#8220;For Google, health equity becomes &#8216;health optimization&#8217; as Trump targets DEI&#8221;</a></p><p><a href="https://www.cnbc.com/2025/07/10/trumps-big-beautiful-bill-cuts-snap-for-millions-of-families.html">&#8220;Trump&#8217;s &#8216;big beautiful bill&#8217; cuts food stamps for millions&#8212;the average family may lose $146 per month, report finds&#8221;</a></p><p><a href="https://www.nytimes.com/2025/07/09/nyregion/trump-domestic-policy-bill-new-york-health-care.html">&#8220;Why 1.5 Million New Yorkers Could Lose Health Insurance Under Trump Bill&#8221;</a></p><p><a href="https://academic.oup.com/healthaffairsscholar/article/3/3/qxae170/8078917">&#8220;The fundamental importance of social insurance for health equity&#8221;</a></p><p><a href="https://www.census.gov/quickfacts/fact/table/US/PST045224">United States Census Bureau: Quick Facts</a></p><p><a href="https://socialwelfare.library.vcu.edu/social-security/social-security-a-brief-history-of-social-insurance/">&#8220;Social Security: A Brief History of Social Insurance&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/39158859/">Seth Berkowitz: &#8220;Expanded Child Tax Credit and Food Insecurity&#8221;</a></p><p><a href="https://www.fns.usda.gov/snap/supplemental-nutrition-assistance-program">USDA: Supplemental Nutrition Assistance Program (SNAP)</a></p><p><a href="https://www.kff.org/medicaid/issue-brief/5-key-facts-about-medicaid-work-requirements/">&#8220;5 Key Facts About Medicaid Work Requirements&#8221;</a></p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/atheendar-venkataramani-opportunity-hope-and-health">Health &amp; Veritas Ep. 125: Atheendar Venkataramani: Opportunity, Hope, and Health</a></p><p>The Budget and Medical Education</p><p><a href="https://www.aamc.org/media/75126/download">&#8220;Examining Long-Term Trends in Reported Tuition and Fees Revenues at U.S. Medical Schools&#8221;</a></p><p><a href="https://store.aamc.org/downloadable/download/sample/sample_id/633/">&#8220;Medical Student Education: Debt, Costs, and Loan Repayment Fact Card for the Class of 2024&#8221;</a></p><p><a href="https://studentaid.gov/understand-aid/types/loans/subsidized-unsubsidized">Department of Education: Direct Subsidized and Direct Unsubsidized Loans</a></p><p><a href="https://studentaid.gov/understand-aid/types/loans/plus/grad">Department of Education: Direct PLUS Loans for Graduate or Professional Students</a></p><p><a href="https://www.nbcnews.com/politics/congress/medical-students-fret-student-loan-cap-big-beautiful-bill-rcna217228">&#8220;Medical students fret over the new student loan cap in the 'big, beautiful bill'&#8220;</a></p><p><a href="https://studentaid.gov/manage-loans/forgiveness-cancellation/public-service">Department of Education: Public Service Loan Forgiveness (PSLF)</a></p><p><a href="https://www.whitehouse.gov/presidential-actions/2025/03/restoring-public-service-loan-forgiveness/">Executive Order: Restoring Public Service Loan Forgiveness</a></p><p><a href="https://www.ed.gov/about/news/press-release/us-department-of-education-concludes-negotiated-rulemaking-session-restore-public-service-loan-forgiveness">&#8220;U.S. Department of Education Concludes Negotiated Rulemaking Session to Restore Public Service Loan Forgiveness&#8221;</a></p><p><a href="https://time.com/7301329/student-loans-forgiveness-pslf-trump-executive-order/">&#8220;How Trump Wants to Reshape a Major Student Loan Forgiveness Program&#8212;and Who Could Be Impacted&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Azita Emami: Educating Nurse-Leaders]]></title><description><![CDATA[Howie and Harlan are joined by Azita Emami, dean of the Yale School of Nursing, to discuss the school&#8217;s approach to training nurses who can have a seat at the table of healthcare decision-making. Harlan reports on his new study showing the low...]]></description><link>https://neverdelegateunderstanding.substack.com/p/azita-emami-educating-nurse-leaders-0e3</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/azita-emami-educating-nurse-leaders-0e3</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 10 Jul 2025 12:25:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298515/f8f8bfa8a03802f0300dc18cd9650cdf.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by Azita Emami, dean of the Yale School of Nursing, to discuss the school&#8217;s approach to training nurses who can have a seat at the table of healthcare decision-making. Harlan reports on his new study showing the low levels of evidence required for medical devices in the FDA&#8217;s Breakthrough Devices Program; Howie provides some good news about infectious diseases including malaria and HIV.</p><p>Links:</p><p>Breakthrough devices?</p><p><a href="https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2835682">Harlan Krumholz: &#8220;FDA Authorization of Therapeutic Devices Under the Breakthrough Devices Program&#8221;</a></p><p><a href="https://www.fda.gov/medical-devices/how-study-and-market-your-device/breakthrough-devices-program">FDA: Breakthrough Devices Program</a></p><p><a href="https://www.statnews.com/2025/06/30/are-fda-breakthrough-devices-really-breakthroughs-new-study-examines-evidence/">&#8220;Many medical devices deemed &#8216;breakthrough&#8217; by FDA are backed by patchy evidence&#8221;</a></p><p><a href="https://www.fda.gov/about-fda/innovation-fda/fda-facts-biomarkers-and-surrogate-endpoints">FDA Facts: Biomarkers and Surrogate Endpoints</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/39284187/">Harlan Krumholz: &#8220;Class I Recalls of Cardiovascular Devices Between 2013 and 2022 : A Cross-Sectional Analysis&#8221;</a></p><p>Azita Emami</p><p><a href="https://news.gallup.com/poll/655106/americans-ratings-professions-stay-historically-low.aspx">&#8220;Americans' Ratings of U.S. Professions Stay Historically Low&#8221;</a></p><p><a href="https://www.washington.edu/news/2013/01/07/university-of-washington-selects-azita-emami-as-dean-of-school-of-nursing/">&#8220;University of Washington selects Azita Emami as dean of School of Nursing&#8221;</a></p><p><a href="https://yaledailynews.com/blog/2023/04/03/azita-emami-named-new-dean-of-school-of-nursing/">&#8220;Azita Emami named new dean of School of Nursing&#8221;</a></p><p><a href="https://www.jstor.org/stable/3407847?seq=1">&#8220;The Report of the Rockefeller Foundation on Nursing Education: A Review and Critique&#8221;</a></p><p><a href="https://my.clevelandclinic.org/health/diagnostics/22148-dheas-test-dhea-sulfate-test">Cleveland Clinic: DHEAS Test</a></p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC8290065/">&#8220;DHEA as a Biomarker of Stress: A Systematic Review and Meta-Analysis&#8221;</a></p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10231046/">Azita Emami: &#8220;Assessing stress using repeated saliva concentration of steroid hormones in dementia care dyads: results from a controlled pilot care music intervention&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/35238213/">Azita Emami: &#8220;The Feasibility and Acceptability of In-Home Saliva Collection for Stress in Persons With Dementia and Their Family Caregivers&#8221;</a></p><p>Infectious diseases</p><p><a href="https://www.mayoclinic.org/diseases-conditions/malaria/symptoms-causes/syc-20351184">Mayo Clinic: Malaria</a></p><p><a href="https://www.who.int/teams/global-malaria-programme/reports/world-malaria-report-2024">WHO: World Malaria Report 2024</a></p><p><a href="https://www.who.int/news/item/23-01-2025-georgia-certified-malaria-free-by-who">&#8220;Georgia certified malaria-free by WHO&#8221;</a></p><p><a href="https://www.who.int/news/item/30-06-2025-suriname-certified-malaria-free-by-who">&#8220;Suriname certified malaria-free by WHO&#8221;</a></p><p><a href="https://www.theglobalfund.org/en/">The Global Fund to Fight AIDS, Tuberculosis and Malaria</a></p><p><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/novartis-gets-approval-first-malaria-drug-babies-children-2025-07-08/">&#8220;Novartis wins approval for first malaria drug for newborns and babies&#8221;</a></p><p><a href="https://time.com/7295343/fda-hiv-shot-lenacapavir-yeztugo/">&#8220;FDA Approves a Twice-Yearly Shot to Prevent HIV&#8221;</a></p><p><a href="https://www.npr.org/sections/shots-health-news/2025/07/09/nx-s1-5461155/measles-outbreak-cdc-vaccination-health">&#8220;U.S. measles cases hit highest level in 33 years, CDC reports&#8221;</a></p><p><a href="https://www.dshs.texas.gov/news-alerts/measles-outbreak-2025">Texas Department of State Health Services: Measles Outbreak</a></p><p><a href="https://www.texasstandard.org/stories/texas-measles-outbreak-slowing-down/">&#8220;The West Texas measles outbreak has started to slow for the first time since January&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[America’s Healthcare Paradox and Other News]]></title><description><![CDATA[Howie and Harlan discuss the alarming healthcare cuts proposed in the budget bill currently moving through Congress, recent breakthroughs in HIV prevention and diabetes treatment, and the stark contrast between scientific progress and the deep...]]></description><link>https://neverdelegateunderstanding.substack.com/p/americas-healthcare-paradox-and-other-fd2</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/americas-healthcare-paradox-and-other-fd2</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 03 Jul 2025 14:20:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298516/9804027b9e46fffb2d98ddf60194a198.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan discuss the alarming healthcare cuts proposed in the budget bill currently moving through Congress, recent breakthroughs in HIV prevention and diabetes treatment, and the stark contrast between scientific progress and the deep structural flaws in the U.S. healthcare system.</p><p>Links:</p><p>The Budget Bill</p><p><a href="https://www.congress.gov/bill/119th-congress/house-bill/1/text">H.R.1&#8212;119th Congress (2025-2026)</a></p><p><a href="https://www.nytimes.com/interactive/2025/06/30/upshot/senate-republican-megabill.html">&#8220;A List of Nearly Everything in the Senate G.O.P. Bill, and How Much It Would Cost or Save&#8221;</a></p><p><a href="https://www.statnews.com/2025/07/01/senate-trump-tax-cut-bill-passes-health-care-impacts-include-medicaid-cuts-health-insurance-coverage/">&#8220;Senate passes Trump&#8217;s tax-cut bill that would slash Medicaid spending&#8221;</a></p><p><a href="https://www.npr.org/sections/shots-health-news/2025/07/02/nx-s1-5453870/senate-republicans-tax-bill-medicaid-health-care">&#8220;5 ways Trump's tax bill will limit health care access&#8221;</a></p><p><a href="https://www.nytimes.com/2025/07/01/us/politics/murkowski-republican-bill.html">&#8220;Murkowski Casts Decisive Vote for G.O.P. Policy Bill, Making an &#8216;Agonizing&#8217; Choice&#8221;</a></p><p><a href="https://www.kff.org/medicaid/issue-brief/mapping-hospital-employment-by-state/#:~:text=Hospitals%20employed%20more%20than%20100%2C000,states%2C%20when%20comparing%20industry%20subsectors">&#8220;Mapping Hospital Employment By State&#8221;</a></p><p><a href="https://www.theatlantic.com/business/archive/2018/01/health-care-america-jobs/550079/">&#8220;Health Care Just Became the U.S.'s Largest Employer&#8221;</a></p><p>The Budget Bill and Universities</p><p><a href="https://provost.yale.edu/news/actions-anticipation-federal-legislation#:~:text=To%20that%20end%2C%20we%20will,role%20in%20advancing%20our%20mission">Yale Office of the Provost: &#8220;Actions in anticipation of federal legislation&#8221;</a></p><p><a href="https://yaledailynews.com/blog/2025/07/01/yale-pauses-hiring-tightens-budget-in-anticipation-of-endowment-tax-hike/">&#8220;Yale pauses hiring, tightens budget in anticipation of endowment tax hike&#8221;</a></p><p><a href="https://www.nytimes.com/2025/06/10/business/yale-endowment-private-equity-trump.html">&#8220;Yale Is Rushing to Sell Billions in Private Equity Investments&#8221;</a></p><p><a href="https://www.nytimes.com/article/trump-university-college.html">&#8220;Trump Has Targeted These Universities. Why?&#8221;</a></p><p><a href="https://www.nytimes.com/2025/05/20/us/universities-endowment-tax-republicans.html">&#8220;Republican Plan to Tax Elite Colleges Could Hit in Unexpected Places&#8221;</a></p><p><a href="https://www.statnews.com/2025/02/08/nih-indirect-research-cost-rate-cuts-universities-threat/">&#8220;The NIH&#8217;s drastic cut to indirect cost rates is a critical threat to U.S. research infrastructure&#8221;</a></p><p>The 340B Drug Program</p><p><a href="https://www.congress.gov/crs-product/IF12232">Congressional Research Service: Overview of the 340B Drug Discount Program</a></p><p><a href="https://www.statnews.com/pharmalot/2025/06/27/jnj-340b-hrsa-hhs-bristol-novartis-lilly-pharma-medicines-medicare-rebates-hospital-clinic/">&#8220;J&amp;J suffers a loss over 340B drug discount program&#8221;</a></p><p><a href="https://www.ajmc.com/view/contributor-beyond-the-sloganeering-a-data-driven-analysis-of-recent-340b-growth">&#8220; Beyond the Sloganeering&#8212;A Data-Driven Analysis of Recent 340B Growth&#8221;</a></p><p><a href="https://www.aha.org/fact-sheets/fact-sheet-340b-drug-pricing-program">American Hospital Association: Fact Sheet: The 340B Drug Pricing Program</a></p><p><a href="https://phrma.org/policy-issues/340b">PhRMA: The 340B Hospital Markup Program</a></p><p>A Stem Cell Treatment for Diabetes</p><p><a href="https://diabetes.org/newsroom/press-releases/stem-cell-derived-islet-therapies-shown-reduce-need-injectable-insulin">&#8220;Stem Cell-Derived Islet Therapies Shown to Reduce the Need for Injectable Insulin&#8221;</a></p><p><a href="https://www.nytimes.com/2025/06/05/health/kennedy-stem-cells-experimental-treatments.html">&#8220;Kennedy Says &#8216;Charlatans&#8217; Are No Reason to Block Unproven Stem Cell Treatments&#8221;</a></p><p><a href="https://www.mayoclinic.org/tests-procedures/bone-marrow-transplant/in-depth/stem-cells/art-20048117">Mayo Clinic: &#8220;Stem cells: What they are and what they do&#8221;</a></p><p><a href="https://my.clevelandclinic.org/health/diseases/7104-diabetes">Cleveland Clinic: Diabetes</a></p><p><a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2506549#:~:text=Our%20study%20showed%20that%20stem,persons%20with%20type%201%20diabetes">&#8220;Stem Cell&#8211;Derived, Fully Differentiated Islets for Type 1 Diabetes&#8221;</a></p><p>Medicare Advantage and the VA</p><p><a href="https://www.wsj.com/health/healthcare/veterans-medicare-insurers-collect-billions-bfd47d27?gaa_at=eafs&amp;gaa_n=ASWzDAixuhG2jmMB2y9Qeev6YNQsYrPNf-1_NpocIZ0tukL_DHPbqnLFQOJ1mCbv6PE%3D&amp;gaa_ts=6865637d&amp;gaa_sig=fxOjtD8Fn2co4mKXktihmS-JynW2cgaUSZvdx5-OAj9bvvo42Oia4cGIeq2WsHIhpABD668Sn8O5cttOvPkVSA%3D%3D">&#8220;Insurers Collected Billions From Medicare for Veterans Who Cost Them Almost Nothing&#8221;</a></p><p><a href="https://www.wsj.com/politics/policy/lawmakers-seek-to-close-va-loophole-that-funnels-billions-to-private-medicare-insurers-cfbe0b19?gaa_at=eafs&amp;gaa_n=ASWzDAgHqoAgVcOzdOOcw6hmdFzBEet5ockLB0S2rdapzl7isAakF28moKVTKOmIT08%3D&amp;gaa_ts=6865637d&amp;gaa_sig=JGlgdFGnecOQxxPQ9z00JxuuYm4OblId29j585K0sNcKYPFrmW01Gw4qP8nhRfQVp0TXvPxpGMQs21lf4xVsuA%3D%3D">&#8220;Lawmakers Seek to Close VA Loophole That Funnels Billions to Private Medicare Insurers&#8221;</a></p><p><a href="https://www.healthaffairs.org/doi/10.1377/hlthaff.2024.00302">&#8220;Medicare Advantage Plans With High Numbers Of Veterans: Enrollment, Utilization, And Potential Wasteful Spending&#8221;</a></p><p>A New HIV Drug</p><p><a href="https://www.hiv.gov/hiv-basics/overview/history/hiv-and-aids-timeline">HIV.gov: A Timeline of HIV and AIDS</a></p><p><a href="https://www.statnews.com/2025/06/18/fda-approves-gilead-hiv-prevention-drug-lenacapavir-yeztugo-next-best-thing-to-vaccine/">&#8220;HIV protection with just two shots a year: FDA approves Gilead drug&#8221;</a></p><p><a href="https://time.com/7298994/usaid-deaths-studies-estimates-foreign-aid-hiv-aids-malaria-sudan/">&#8220;Shuttering of USAID Will Lead to Millions of Deaths Around the World: Studies&#8221;</a></p><p><a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01186-9/fulltext">&#8220;Evaluating the impact of two decades of USAID interventions and projecting the effects of defunding on mortality up to 2030: a retrospective impact evaluation and forecasting analysis&#8221;</a></p><p>Kennedy v. Braidwood</p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/abbe-gluck-the-legal-determinants-of-health">Health &amp; Veritas Episode 84: Abbe Gluck: The Legal Determinants of Health</a></p><p><a href="https://www.supremecourt.gov/opinions/24pdf/24-316_869d.pdf">Supreme Court opinion: KENNEDY, SECRETARY OF HEALTH AND HUMAN SERVICES, ET AL. v. BRAIDWOOD MANAGEMENT, INC., ET AL.</a></p><p><a href="https://www.kff.org/policy-watch/kennedy-v-braidwood-the-supreme-court-upheld-aca-preventive-services-but-thats-not-the-end-of-the-story/">&#8220;Kennedy v. Braidwood: The Supreme Court Upheld ACA Preventive Services but That&#8217;s Not the End of the Story&#8221;</a></p><p><a href="https://www.healthaffairs.org/content/forefront/supreme-court-upholds-preventive-services-requirement-under-aca">&#8220;Supreme Court Upholds Preventive Services Requirement Under ACA&#8221;</a></p><p>The Big Picture for U.S. Healthcare</p><p><a href="https://paulkeckley.com/the-keckley-report/2025/6/29/the-perfect-storm-has-hit-u-s-healthcare/">&#8220;The Perfect Storm has Hit U.S. Healthcare&#8221;</a></p><p><a href="https://www.healthaffairs.org/doi/full/10.1377/hlthaff.2025.00545">&#8220;National Health Expenditure Projections, 2024&#8211;33: Despite Insurance Coverage Declines, Health To Grow As Share Of GDP&#8221;</a></p><p>Exercise and Cancer</p><p><a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2502760">&#8220;Structured Exercise after Adjuvant Chemotherapy for Colon Cancer&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Stephen Waxman: Easing the Horrors of Chronic Pain]]></title><description><![CDATA[Howie and Harlan are joined by Stephen Waxman, a leading neurology researcher, to discuss the promise of new methods developed by his lab to treat the ravages of pain. Harlan talks about the importance of ratings for Medicare Advantage plans; Howie...]]></description><link>https://neverdelegateunderstanding.substack.com/p/stephen-waxman-easing-the-horrors-ab1</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/stephen-waxman-easing-the-horrors-ab1</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 26 Jun 2025 11:20:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298517/16f81892a5612e06513dd9c51b4f8361.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by Stephen Waxman, a leading neurology researcher, to discuss the promise of new methods developed by his lab to treat the ravages of pain. Harlan talks about the importance of ratings for Medicare Advantage plans; Howie assesses two sobering new reports on the solvency of Medicare.</p><p>Links:</p><p>Harlan&#8217;s Section</p><p><a href="https://humana.gcs-web.com/static-files/1eed73bd-c41f-4d21-9cee-ca94a8b9c945">&nbsp;Slides from Humana's Investor Day</a></p><p><a href="https://www.healthcaredive.com/news/humana-defends-medicare-advantage-investor-day/750872/">&nbsp;"Humana&#8217;s cautious defense of Medicare Advantage"</a></p><p><a href="https://www.ncoa.org/article/medicare-star-ratings/">"What Are the Medicare Star Ratings?"</a></p><p><a href="https://www.healthscape.com/insights/early-analysis-how-health-plans-fared-in-the-2025-medicare-advantage-star-ratings">&nbsp;"Early analysis: How health plans fared in the 2025 Medicare Advantage star ratings"</a></p><p>Interview with Dr. Waxman</p><p><a href="https://www.nytimes.com/2025/01/30/health/fda-journavx-suzetrigine-vertex-opioids.html">&nbsp;"F.D.A. Approves Drug to Treat Pain Without Opioid Effects"</a></p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3424716/">"A brief historical perspective: Hodgkin and Huxley"</a></p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC1392413/">"A quantitative description of membrane current and its application to conduction and excitation in nerve"</a></p><p><a href="https://www.nobelprize.org/prizes/medicine/1963/speedread/">Nobel Prize: &#8220;Speed read: Signal to charge"</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/10393872/">"Sodium channels and pain"</a></p><p><a href="https://www.nejm.org/doi/10.1056/NEJMe2305708">"Targeting a Peripheral Sodium Channel to Treat Pain"</a></p><p><a href="https://millenniumtrilogy.fandom.com/wiki/Ronald_Niedermann">Girl with the Dragon Tattoo: "Ronald Niedermann"</a></p><p><a href="https://medicine.yale.edu/news-article/peripheral-sodium-channel-blocker-could-revolutionize-treatment-for-nerve-pain/">&nbsp;"Peripheral Sodium Channel Blocker Could Revolutionize Treatment for Nerve Pain"</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/39378238/">"Interplay of Nav1.8 and Nav1.7 channels drives neuronal hyperexcitability in neuropathic pain"</a></p><p><a href="https://jamanetwork.com/journals/jamaneurology/fullarticle/2514552">&nbsp;"Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling"</a></p><p><a href="https://my.clevelandclinic.org/health/diseases/15833-neuropathic-pain">&nbsp;"Neuropathic Pain"</a></p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3108295/">"A historical perspective on the discovery of statins"</a></p><p><a href="https://my.clevelandclinic.org/health/diseases/22752-erythromelalgia">&nbsp;"Erythromelalgia"</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/30844393/">"The Two Sides of NaV1.7: Painful and Painless Channelopathies"</a></p><p><a href="https://www.research.va.gov/about/awards/awardee.cfm?award=258184">&nbsp;"Dr. Stephen Waxman awarded Sharpey-Schafer Prize for pain research"</a></p><p><a href="https://www.nobelprize.org/prizes/medicine/2010/edwards/facts/">Nobel Prize: "Robert Edwards"</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/15958509/">"Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons"</a></p><p><a href="https://medicine.yale.edu/news-article/scientists-identify-method-to-study-resilience-to-pain/">&nbsp;"Scientists Identify Method to Study Resilience to Pain"</a></p><p><a href="https://knowablemagazine.org/content/article/health-disease/2020/genetic-causes-of-pain">&nbsp;"Chasing the genes behind pain"</a></p><p><a href="https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(18)30393-4/fulltext">&nbsp;"Stephen Waxman: pioneer in axons, their disorders, and pain"</a></p><p><a href="https://time.com/6257668/man-on-fire-syndrome-erythromelalgia/">"I Feel Like I&#8217;m Burning Alive. It&#8217;s Hard for People to Believe Me"</a></p><p><a href="https://www.clinicaltrialsarena.com/features/pain-endpoints-clinical-trials/">&nbsp;"&#8216;How badly does it hurt?&#8217; Challenges of measuring pain in clinical trials"</a></p><p>Howie&#8217;s Section</p><p><a href="https://www.cms.gov/oact/tr/2025">"2025 Medicare Trustees Report"</a></p><p><a href="https://www.crfb.org/papers/analysis-2025-medicare-trustees-report">&nbsp;"Analysis of the 2025 Medicare Trustees' Report"</a></p><p><a href="https://www.statnews.com/2025/04/05/medicare-hospital-insurance-trust-fund-cbo-estimate-2052/">&nbsp;"Medicare gets a big (unofficial) surprise: a 17-year extension on when it&#8217;ll run dry"</a></p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/evan-sussman-expanding-access-to-fertility-drugs">&nbsp;"Evan Sussman: Expanding Access to Fertility Drugs"</a></p><p><a href="https://www.statnews.com/2025/04/07/medicare-advantage-payment-rate-2026-cms-trump/">&nbsp;"Trump gives major lift to 2026 Medicare Advantage payments"</a></p><p><a href="https://www.medpac.gov/document/june-2025-report-to-the-congress-medicare-and-the-health-care-delivery-system/">&nbsp;"June 2025 Report to the Congress: Medicare and the Health Care Delivery System"</a></p><p><a href="https://www.statnews.com/2025/06/12/medicare-advantages-supplemental-benefits-cost-86-billion-little-transparency/">&nbsp;"Medicare Advantage&#8217;s supplemental benefits will cost taxpayers $86 billion this year, with little transparency"</a></p><p><a href="https://www.statnews.com/2024/08/07/unitedhealth-peripheral-artery-disease-screening-program-medicare-advantage-gold-mine/">&nbsp;"How UnitedHealth turned a questionable artery-screening program into a gold mine"</a></p><p><a href="https://www.statnews.com/2025/06/24/semler-scientific-pivots-to-bitcoin-quantaflo-artery-test-doj-scrutiny-medicare-advantage/">&nbsp;"From boom to bitcoin: A device maker&#8217;s surprising pivot amid a Medicare crackdown"</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[The ‘Big Beautiful Bill’ and Other News]]></title><description><![CDATA[Howie and Harlan discuss health and healthcare issues making headlines, including public attitudes toward the Medicaid cuts in the budget bill making its way through Congress, a one-time gene therapy that could cure high cholesterol, &#8220;ambient&#8221; AI...]]></description><link>https://neverdelegateunderstanding.substack.com/p/the-big-beautiful-bill-and-other-8d3</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/the-big-beautiful-bill-and-other-8d3</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 19 Jun 2025 14:19:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298518/21eefc1b87dedc7f9bc1d384872f48dd.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan discuss health and healthcare issues making headlines, including public attitudes toward the Medicaid cuts in the budget bill making its way through Congress, a one-time gene therapy that could cure high cholesterol, &#8220;ambient&#8221; AI in the exam room, and the replacement of the the CDC&#8217;s entire vaccine advisory board.&nbsp;</p><p>Links:</p><p>Remembering Atul Butte</p><p><a href="https://www.fiercehealthcare.com/health-tech/atul-butte-computational-bioinformatics-pioneer-dies-55">&#8220;Atul Butte, a biomedical and bioinformatics pioneer, dies at 55&#8221;</a></p><p><a href="https://www.linkedin.com/posts/marina-sirota-a2736a2_it-is-with-deep-sadness-that-i-write-about-activity-7339981057942765569-XQF2?utm_source=share&amp;utm_medium=member_desktop&amp;rcm=ACoAAEPgwSABe3hlv_yEo3c_izfRscdOMxI1Mh8">Marina Sirota on LinkedIn</a></p><p><a href="https://chancellor.ucsf.edu/news/remembering-atul-butte-md-phd">&#8220;Remembering Atul Butte, MD, PhD&#8221;</a></p><p>The Budget Bill</p><p><a href="https://www.congress.gov/bill/119th-congress/house-bill/1/text">H.R.1&#8212;One Big Beautiful Bill Act</a></p><p><a href="https://www.kff.org/medicaid/poll-finding/kff-health-tracking-poll-views-of-the-one-big-beautiful-bill/">&#8220;KFF Health Tracking Poll: Views of the One Big Beautiful Bill&#8221;</a></p><p><a href="https://www.cbo.gov/publication/61486">CBO: Dynamic Estimate of H.R. 1, One Big Beautiful Bill Act</a></p><p><a href="https://www.reuters.com/article/business/healthcare-pharmaceuticals/protesters-disrupt-town-hall-healthcare-talks-idUSTRE5765QH/">&#8220;Protesters disrupt town-hall healthcare talks&#8221;</a></p><p>Vinay Prasad</p><p><a href="https://www.statnews.com/2025/06/18/vinay-prasad-fda-cber-chief-medical-science-officer-advise-makary/">&#8220;Vinay Prasad named chief medical and science officer at FDA&#8221;</a></p><p><a href="https://apnews.com/article/vinay-prasad-fda-vaccines-kennedy-8bbdc172215a9ba1cd587733b1732bbf">&#8220;Critic of drug industry and COVID-19 measures to lead FDA vaccine program&#8221;</a></p><p>Medicaid Cuts</p><p><a href="https://www.politico.com/live-updates/2025/06/16/congress/senate-gop-tax-bill-would-hit-politically-explosive-medicaid-provision-00408630">&#8220;Senate GOP tax bill would hit politically explosive Medicaid provision&#8221;</a></p><p><a href="https://www.nytimes.com/2025/06/17/upshot/medicaid-cuts-republicans-senate.html">&#8220;The Senate Wants Billions More in Medicaid Cuts, Pinching States and Infuriating Hospitals&#8221;</a></p><p><a href="https://www.kff.org/medicaid/issue-brief/5-key-facts-about-medicaid-work-requirements/">&#8220;5 Key Facts About Medicaid Work Requirements&#8221;</a></p><p><a href="https://www.propublica.org/article/georgia-medicaid-work-requirement-pathways-to-coverage-hurdles">&#8220;Georgia Touts Its Medicaid Experiment as a Success. The Numbers Tell a Different Story.&#8221;</a></p><p><a href="https://gbpi.org/georgias-pathways-to-coverage-program-the-first-year-in-review/">&#8220;Georgia&#8217;s Pathways to Coverage Program: The First Year in Review&#8221;</a></p><p><a href="https://www.nytimes.com/interactive/2025/06/12/upshot/gop-megabill-distribution-poor-rich.html">&#8220;Trump&#8217;s Big Bill Would Be More Regressive Than Any Major Law in Decades&#8221;</a></p><p>Gene Therapy to Prevent Heart Disease</p><p><a href="https://www.vervetx.com/">Verve Therapeutics</a></p><p><a href="https://www.vervetx.com/about-us/meet-our-team/sekar-kathiresan-md">Verve Therapeutics: Sekar Kathiresan, M.D.</a></p><p><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/eli-lilly-nears-13-billion-deal-gene-editing-biotech-verve-therapeutics-ft-2025-06-16/">&#8220;Lilly to buy gene-editing partner Verve for up to $1.3 billion in cardiac care push&#8221;</a></p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10177981/">&#8220;Viral Vector-Based Gene Therapy&#8221;</a></p><p><a href="https://www.nature.com/articles/s41392-022-01007-w">&#8220;mRNA-based therapeutics: powerful and versatile tools to combat diseases&#8221;</a></p><p><a href="https://apnews.com/article/sarepta-muscular-dystophy-duchennes-gene-therapy-255d04aa3db9bd171c9bf006328ba5d3">&#8220;Second patient death reported with gene therapy for muscular dystrophy&#8221;</a></p><p>Anti-Vaxxers at the CDC</p><p><a href="https://insidemedicine.substack.com/p/scoop-cdc-has-no-acting-director">&#8220;Scoop: CDC has no Acting Director, sources confirm.&#8221;</a></p><p><a href="https://x.com/highbrow_nobrow/status/1933928731740881327?ref_src=twsrc%5Etfw%7Ctwcamp%5Etweetembed%7Ctwterm%5E1933928731740881327%7Ctwgr%5Ef75a9d3c47ff28358ca30a7d02a5aa4ff4d0b604%7Ctwcon%5Es1_&amp;ref_url=https%3A%2F%2Fwww.dailymail.co.uk%2Fhealth%2Farticle-14820721%2Frobert-f-kennedy-jr-RFK-polio-vaccine-claim.html">Video: Robert F. Kennedy Jr. on the polio vaccine</a></p><p><a href="https://www.technologyreview.com/2021/10/05/1036408/silicon-valley-millionaire-steve-kirsch-covid-vaccine-misinformation/">&#8220;This tech millionaire went from covid trial funder to misinformation superspreader&#8221;</a></p><p><a href="https://www.nytimes.com/2025/06/09/health/rfk-jr-cdc-vaccine-panel.html">&#8220;Kennedy Removes All C.D.C. Vaccine Panel Experts&#8221;</a></p><p><a href="https://www.npr.org/sections/shots-health-news/2025/06/13/nx-s1-5429604/cdc-rfk-acip-vaccine-committee">&#8220;RFK Jr. replaced everyone on the CDC's vaccine panel. Here's why that matters&#8221;</a></p><p><a href="https://www.kff.org/other/issue-brief/acip-cdc-and-insurance-coverage-of-vaccines-in-the-united-states/">&#8220;ACIP, CDC, and Insurance Coverage of Vaccines in the United States&#8221;</a></p><p>Ambient AI</p><p><a href="https://www.forbes.com/sites/saibala/2024/08/26/ambient-ai-is-having-its-moment-in-healthcare/">&#8220;Ambient AI Is Having Its &#8216;Moment&#8217; In Healthcare&#8221;</a></p><p><a href="https://www.washingtonpost.com/opinions/2025/03/25/ambient-ai-health-care-artificial-intelligence/">&#8220;This technology is becoming beloved by doctors and patients alike&#8221;</a></p><p><a href="https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831866">&#8220;Physician Perspectives on Ambient AI Scribes&#8221;</a></p><p><a href="https://www.cnbc.com/2025/03/03/microsoft-unveils-dragon-copilot-a-voice-activated-ai-tool-for-doctors-.html">&#8220;Microsoft unveils new voice-activated AI assistant for doctors&#8221;</a></p><p><a href="https://www.fiercehealthcare.com/health-tech/kaiser-permanente-rolls-out-abridges-gen-ai-clinical-tech-across-40-hospitals-60">&#8220;Kaiser Permanente rolls out Abridge's gen AI clinical tech across 40-hospital system&#8221;</a></p><p><a href="https://www.bloomberg.com/news/articles/2025-05-30/andreessen-horowitz-in-funding-talks-valuing-abridge-ai-at-5-3-billion">&#8220;Andreessen Horowitz in Deal Talks Valuing Abridge AI at $5.3 Billion&#8221;</a></p><p><a href="https://www.ynhhs.org/perspectives/abridge-easing-workload">&#8220;Abridge easing clinician workload&#8221;</a></p>]]></content:encoded></item><item><title><![CDATA[Sarah DeSilvey: Creating Space for Healing]]></title><description><![CDATA[Howie and Harlan are joined by Sarah DeSilvey to talk about her career as a rural nurse practitioner and her work to create a shared vocabulary for tracking social determinants of health. Harlan unpacks the research implications of the &#8220;big...]]></description><link>https://neverdelegateunderstanding.substack.com/p/sarah-desilvey-creating-space-for-067</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/sarah-desilvey-creating-space-for-067</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 12 Jun 2025 15:42:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298519/ae05f17c6e39e23e9268aa42065997f1.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by Sarah DeSilvey to talk about her career as a rural nurse practitioner and her work to create a shared vocabulary for tracking social determinants of health. Harlan unpacks the research implications of the &#8220;big beautiful bill&#8221; in Congress, and reports on his new research about the link between state gun laws and deaths among children; Howie discusses the simple steps that can prevent syphilis from being passed from mothers to babies in utero.&nbsp;</p><p>Links:</p><p>Budget Cuts</p><p><a href="https://www.statnews.com/2025/06/10/nih-senators-push-back-on-2026-trump-budget-jay-bhattacharya/">&#8220;Senators push back on Trump&#8217;s proposed $18 billion NIH budget cut&#8221;</a></p><p><a href="https://www.congress.gov/bill/119th-congress/house-bill/1/text">&#8220;H.R.1&#8212;One Big Beautiful Bill Act&#8221;</a></p><p><a href="https://www.statnews.com/2025/06/06/nih-cuts-newly-released-documents-detail-impact-on-grants-training-research-labs/">&#8220;NIH details how Trump budget would cut support for grants, training, and research centers&#8221;</a><a href="https://www.cbsnews.com/news/nih-layoffs-budget-cuts-medical-research-60-minutes/">&#8220;How cuts at the National Institutes of Health could impact Americans' health&#8221;</a></p><p><a href="https://jamanetwork.com/journals/jama/fullarticle/2833880?guestAccessKey=3a432109-6c9d-4ef2-9d10-bf48d91fe441&amp;utm_source=for_the_media&amp;utm_medium=referral&amp;utm_campaign=ftm_links&amp;utm_content=tfl&amp;utm_term=050825#250325688">Harlan Krumholz: &#8220;Characterization of Research Grant Terminations at the National Institutes of Health&#8221;</a></p><p>Guns and Kids</p><p><a href="https://pubmed.ncbi.nlm.nih.gov/40489107/">Harlan Krumholz: &#8220;Firearm Laws and Pediatric Mortality in the US&#8221;</a></p><p><a href="https://insidemedicine.substack.com/">Jeremy Faust: Inside Medicine</a></p><p><a href="https://www.oyez.org/cases/2009/08-1521">McDonald v. City of Chicago</a>&nbsp;</p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/james-dodington-protecting-kids-from-gun-violence">Health &amp; Veritas Episode 174: James Dodington: Protecting Kids from Gun Violence</a></p><p>Sarah DeSilvey</p><p><a href="https://thegravityproject.net/">The Gravity Project</a></p><p><a href="https://www.cdc.gov/about/priorities/why-is-addressing-sdoh-important.html">CDC: Social Determinants of Health (SDOH)</a></p><p><a href="https://www.fns.usda.gov/wic">WIC: USDA's Special Supplemental Nutrition Program for Women, Infants, and Children</a></p><p><a href="https://www.cbpp.org/research/food-assistance/wic-works-addressing-the-nutrition-and-health-needs-of-low-income-families">&#8220;WIC Works: Addressing the Nutrition and Health Needs of Low-Income Families for More Than Four Decades&#8221;</a></p><p><a href="https://www.cbpp.org/blog/trump-budget-would-slash-wic-fruit-and-vegetable-benefits-for-millions">&#8220;Trump Budget Would Slash WIC Fruit and Vegetable Benefits for Millions&#8221;</a></p><p><a href="https://www.hl7.org/">Health Level 7L7</a></p><p>Congenital Syphilis</p><p><a href="https://www.cdc.gov/mmwr/volumes/74/wr/mm7420a3.htm">&#8220;Missed Opportunities for Congenital Syphilis Prevention&#8212;Clark County, Nevada, 2017&#8211;2022&#8221;</a></p><p><a href="https://www.cdc.gov/mmwr/index.html">CDC: Mortality and Morbidity Weekly Report</a></p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/dave-chokshi-lessons-from-the-front-lines-of-the-pandemic">Health &amp; Veritas Episode 1777: Dave Chokshi: Lessons from the Front Lines of the Pandemic</a></p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/manisha-juthani-solving-infectious-disease-mysteries">Health &amp; Veritas Epoisode 155: Manisha Juthani: Solving Infectious Disease Mysteries</a></p><p><a href="https://my.clevelandclinic.org/health/diseases/congenital-rubella-syndrome">Cleveland Clinic: Congenital rubella syndrome</a></p><p><a href="https://www.cdc.gov/sti-statistics/data-vis/table-syph-congenital-yearstate-abc.html">CDC: Congenital Syphilis&#8212;Reported Cases and Rates of Reported Cases by Year of Birth, by State/Territory and Region in Alphabetical Order, United States</a></p>]]></content:encoded></item><item><title><![CDATA[Dave Chokshi: Lessons from the Front Lines of the Pandemic]]></title><description><![CDATA[Howie and Harlan are joined by Dave Chokshi, who led New York City&#8217;s response to COVID-19 as health commissioner and serves as chair of the Common Health Coalition, which is working to prepare for future crises by strengthening partnerships between...]]></description><link>https://neverdelegateunderstanding.substack.com/p/dave-chokshi-lessons-from-the-front-00b</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/dave-chokshi-lessons-from-the-front-00b</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 05 Jun 2025 13:41:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298520/e94bfd8d81670a0e7a80e588e625cd53.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by Dave Chokshi, who led New York City&#8217;s response to COVID-19 as health commissioner and serves as chair of the Common Health Coalition, which is working to prepare for future crises by strengthening partnerships between healthcare and public health. Harlan reports on a trip to China; Howie says it&#8217;s time for a global effort to expand rubella vaccination.&nbsp;</p><p>Links:</p><p>Harlan in China</p><p><a href="https://medicine.yale.edu/core/projects/china/publications/">Harlan Krumholz: Yale China Project</a></p><p><a href="https://medicine.yale.edu/news/yale-medicine-magazine/article/03-fn-harlan-krumholz/">Harlan Krumholz receives China&#8217;s Friendship Award</a></p><p><a href="https://www.economist.com/science-and-technology/2024/06/12/china-has-become-a-scientific-superpower">&#8220;China has become a scientific superpower&#8221;</a></p><p>Dave Chokshi</p><p><a href="https://commonhealthcoalition.org/">Common Health Coalition</a></p><p><a href="https://catalyst.nejm.org/doi/full/10.1056/CAT.24.0270">Dave Chokshi: &#8220;Public Health and Care Delivery&#8212;a Common Destiny&#8221;</a></p><p><a href="https://commonhealthcoalition.org/challenge/">Common Health Coalition Challenge</a></p><p><a href="https://commonhealthcoalition.org/wp-content/uploads/2025/04/Catalyst-Awards-Press-Release_4.22.25.pdf">&#8220;Common Health Coalition Announces Awards of More Than $400,000 Through Inaugural Common Health Challenge&#8221;</a></p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10817860/">Harlan Krumholz: &#8220;State-Level Excess Mortality and Potential Deaths Averted in US Adults During the Delta and Omicron Waves of COVID-19&#8221;</a></p><p><a href="https://www.nytimes.com/2022/03/14/nyregion/chokshi-leaving-health-nyc.html">&#8220;New York&#8217;s Vaccine Mandates Saved Lives, Departing Health Boss Says&#8221;</a></p><p><a href="https://www.bmj.com/collections/us-covid-series">BMJ series: &#8220;US covid-19 lessons for future health protection and preparedness&#8221;</a></p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/rebekah-gee-improving-health-one-family-at-time">Health &amp; Veritas Episode 175: Rebekah Gee: Improving Health, One Family at a Time</a></p><p><a href="https://www.americanprogress.org/article/hurricane-katrinas-health-care-legacy/">Center for American Progress: Hurricane Katrina&#8217;s Health Care Legacy</a></p><p><a href="https://www.nychealthandhospitals.org/">NYC Health + Hospitals</a></p><p><a href="https://nychealthandhospitals-appservice-test.azurewebsites.net/pressrelease/dave-chokshi-md-is-appointed-chief-population-health-officer-of-nyc-health-hospitals/">&#8220;Dave Chokshi, MD, Is Appointed Chief Population Health Officer of NYC Health + Hospitals&#8221;</a></p><p><a href="https://health.clevelandclinic.org/should-you-be-worried-about-blood-clots-with-covid-19">&#8220;The Connection Between COVID-19 and Blood Clots&#8221;</a></p><p><a href="https://www1.cuny.edu/mu/forum/2025/01/30/ccny-receives-500000-grant-to-incubate-health-leadership-institute/">&#8220;CCNY receives $500,000 grant to incubate health leadership institute&#8221;</a></p><p><a href="https://www.ccny.cuny.edu/news/former-new-york-city-health-commissioner-named-sternberg-family-professor-leadership">&#8220;Former New York City Health Commissioner Named Sternberg Family Professor of Leadership&#8221;</a></p><p><a href="https://www.nytimes.com/2023/09/28/opinion/aging-public-health-healthspan.html">Dave Chokshi: &#8220;Forget About Living to 100. Let&#8217;s Live Healthier Instead.&#8221;</a></p><p>Rubella</p><p><a href="https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-20-rubella.html">CDC: Rubella</a></p><p><a href="https://my.clevelandclinic.org/health/diseases/congenital-rubella-syndrome">Cleveland Clinic: Congenital rubella syndrome</a></p><p><a href="https://www.cdc.gov/rubella/vaccines/index.html#:~:text=For%20rubella%3A%20MMR%20vaccine%20prevents,if%20the%20mother%20gets%20rubella">CDC: Rubella Vaccination</a></p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC12097546/">&#8220;Estimated Current and Future Congenital Rubella Syndrome Incidence with and Without Rubella Vaccine Introduction &#8212; 19 Countries, 2019&#8211;2055&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Live at the Yale Innovation Summit 2025]]></title><description><![CDATA[In a special episode recorded at Connecticut&#8217;s largest entrepreneurship event, Howie and guest host Megan Ranney, the dean of the Yale School of Public Health, welcome four Yale innovators: entrepreneur and YSPH lecturer Kaakpema &#8220;KP&#8221; Yelpaala;...]]></description><link>https://neverdelegateunderstanding.substack.com/p/live-at-the-yale-innovation-summit-519</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/live-at-the-yale-innovation-summit-519</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Fri, 30 May 2025 19:50:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298521/25e3bad75cf6c4dbdafd559a61171c79.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>In a special episode recorded at Connecticut&#8217;s largest entrepreneurship event, Howie and guest host Megan Ranney, the dean of the Yale School of Public Health, welcome four Yale innovators: entrepreneur and YSPH lecturer Kaakpema &#8220;KP&#8221; Yelpaala; Basmah Safdar, incoming director of Women&#8217;s Health Research at Yale; Kayla Wooley, a YSPH graduate and the founder of two nursing home staffing companies; and Yale College student Laurie Jimenez, founder of FulcrumCare, a value-based dental provider for Medicaid and Medicare patients.&nbsp;</p><p>Links:</p><p>The Yale Innovation Summit</p><p><a href="https://ventures.yale.edu/events/yale-innovation-summit-2025">Yale Innovation Summit 2025</a></p><p><a href="https://ventures.yale.edu/">Yale Ventures</a></p><p>Kaakpema &#8220;KP&#8221; Yelpaala</p><p><a href="https://ysph.yale.edu/news-article/public-health-innovator-kaakpema-yelpaala-appointed-senior-fellow-and-lecturer-at-ysph/">&#8220;Public health innovator Kaakpema Yelpaala appointed senior fellow and lecturer at YSPH&#8221;</a></p><p><a href="https://ysph.yale.edu/innovate-health-yale/about/">InnovateHealth Yale</a></p><p><a href="https://www.cityblock.com/">Cityblock</a></p><p><a href="https://girleffect.org/">Girl Effect</a></p><p>Basmah Safdar</p><p><a href="https://medicine.yale.edu/news-article/basmah-safdar-md-facep-appointed-director-womens-health-research-at-yale-whry/">&#8220;Basmah Safdar, MD, FACEP, Appointed Director, Women&#8217;s Health Research at Yale (WHRY)&#8221;</a></p><p><a href="https://medicine.yale.edu/whr/">Women's Health Research at Yale</a></p><p><a href="https://news.yale.edu/2018/02/19/heart-attack-symptoms-often-misinterpreted-younger-women">&#8220;Heart attack symptoms often misinterpreted in younger women&#8221;</a></p><p><a href="https://medicine.yale.edu/news-article/sex-differences-in-covid-19-immune-responses-affect-patient-outcomes/">&#8220;Sex Differences in COVID-19 Immune Responses Affect Patient Outcomes&#8221;</a></p><p><a href="https://www.nytimes.com/2024/09/12/well/live/man-flu-sickness-symptoms.html">&#8220;The Truth About &#8216;Man Flu&#8217;&#8221;</a></p><p><a href="https://www.nytimes.com/2013/01/11/health/fda-requires-cuts-to-dosages-of-ambien-and-other-sleep-drugs.html">&#8220;Drug Agency Recommends Lower Doses of Sleep Aids for Women&#8221;</a></p><p>Kayla Wooley</p><p><a href="https://staffontap.org/">StaffOnTap</a></p><p><a href="https://ysph.yale.edu/news-article/nursing-home-staff-shortages-prompted-ysph-alumna-to-form-two-companies/">&#8220;Nursing home staff shortages prompted YSPH alumna to form two companies&#8221;</a></p><p><a href="https://www.nytimes.com/2024/02/29/health/nursing-home-staffing-shortages-pandemic.html">&#8220;Nursing Home Staffing Shortages and Other Problems Persist, U.S. Report Says&#8221;</a></p><p><a href="https://www.ahcancal.org/News-and-Communications/Press-Releases/Pages/State-Of-The-Sector-Nursing-Home-Staffing-Shortages-Persist-Despite-Unprecedented-Efforts-To-Attract-More-Staff-.aspx">&#8220;State Of The Sector: Nursing Home Labor Staffing Shortages Persist Despite Unprecedented Efforts To Attract More Staff&#8221;</a></p><p><a href="https://www.hingehealth.com/">Hinge Health</a></p><p>Laurie Jimenez</p><p><a href="https://www.getfulcrumcare.com/">FulcrumCare</a></p><p><a href="https://www.commonwealthfund.org/blog/2025/many-medicare-beneficiaries-dental-insurance-face-financial-barriers-care">&#8220;Many Medicare Beneficiaries with Dental Insurance Face Financial Barriers to Care&#8221;</a></p><p><a href="https://www.kff.org/medicaid/issue-brief/variation-in-use-of-dental-services-by-children-and-adults-enrolled-in-medicaid-or-chip/">&#8220;Variation in Use of Dental Services by Children and Adults Enrolled in Medicaid or CHIP&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Rebekah Gee: Improving Health, One Family at a Time]]></title><description><![CDATA[Howie and Harlan are joined by Rebekah Gee, founder and CEO of Nest Health, which provides in-home care to kids on Medicaid and their families. Harlan reports on the first personalized CRISPR gene therapy for a rare genetic disease; Howie untangles...]]></description><link>https://neverdelegateunderstanding.substack.com/p/rebekah-gee-improving-health-one-bfc</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/rebekah-gee-improving-health-one-bfc</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 22 May 2025 13:16:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298522/95eed9c6905eb44f75da082dba01765c.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by Rebekah Gee, founder and CEO of Nest Health, which provides in-home care to kids on Medicaid and their families. Harlan reports on the first personalized CRISPR gene therapy for a rare genetic disease; Howie untangles the FDA&#8217;s restrictions on the COVID-19 booster and what it will mean for your ability to get a shot this fall.&nbsp;</p><p>Links:</p><p>A Breakthrough CRISPR Treatment</p><p><a href="https://www.nytimes.com/2025/05/15/health/gene-editing-personalized-rare-disorders.html">&#8220;Baby Is Healed With World&#8217;s First Personalized Gene-Editing Treatment&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/40373211/">&#8220;Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease&#8221;</a></p><p><a href="https://www.nejm.org/doi/10.1056/NEJMe2505704">&#8220;Progress in the Development of N-of-1 Therapy&#8221;</a></p><p><a href="https://www.nejm.org/doi/full/10.1056/NEJMe2505721">&#8220;Personalized Gene Editing to Treat an Inborn Error of Metabolism&#8221;</a></p><p>Nest Health</p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/dr-rebekah-gee-can-we-bring-family-healthcare-to-the-home">Health &amp; Veritas Episode 40: Rebekah Gee: Can We Bring Family Healthcare to the Home?</a></p><p><a href="https://www.nesthealth.com/">Nest Health</a></p><p><a href="https://www.fiercehealthcare.com/digital-health/nest-health-picks-4m-new-funding-build-out-home-primary-care-families">&#8220;Nest Health picks up $4M in seed extension funding to build out at-home primary care for families&#8221;</a></p><p><a href="https://www.springtide.com/company-highlights/how-nest-health-is-redefining-primary-care-for-families#:~:text=93%25%20of%20patient%20calls%20are,the%20complex%20needs%20of%20families">&#8220;How Nest Health Is Redefining Primary Care for Families&#8221;</a></p><p>Rebekah Gee on LinkedIn on Nest Health</p><p><a href="https://pubmed.ncbi.nlm.nih.gov/19454528/">&#8220;What &#8216;patient-centered&#8216; should mean: confessions of an extremist&#8221;</a></p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6143066/#:~:text=opportunities%20for%20improvement%3F-,Findings,professional%20in%20the%20past%20year.">&#8220;Prevalence and Variation of Developmental Screening and Surveillance in Early Childhood&#8221;</a></p><p><a href="https://harvardpublichealth.org/alumni-post/abandoned-after-birth/">&#8220;Postpartum health is in crisis&#8221;</a></p><p><a href="https://www.kff.org/medicaid/issue-brief/the-impact-of-the-pandemic-on-well-child-visits-for-children-enrolled-in-medicaid-and-chip/">&#8220;The Impact of the Pandemic on Well-Child Visits for Children Enrolled in Medicaid and CHIP&#8221;</a></p><p><a href="https://www.heart.org/en/news/2024/04/17/families-often-have-chief-medical-officers-and-theyre-almost-always-women">&#8220;Families often have chief medical officers&#8212;and they're almost always women&#8221;</a></p><p><a href="https://www.commonwealthfund.org/publications/newsletter-article/case-study-louisianas-poor-rankings-make-improving-birth-outcomes">&#8220;Case Study: Louisiana's Poor Rankings Make Improving Birth Outcomes a State Imperative&#8221;</a></p><p><a href="https://www.nytimes.com/2022/06/24/us/roe-wade-overturned-supreme-court.html">&#8220;In 6-to-3 Ruling, Supreme Court Ends Nearly 50 Years of Abortion Rights&#8221;</a></p><p><a href="https://www.linkedin.com/posts/rebekahgeemd_proposal-cutting-medicaid-aims-for-gop-middle-activity-7327679030411821056-BFAL?utm_source=share&amp;utm_medium=member_desktop&amp;rcm=ACoAAEPgwSABe3hlv_yEo3c_izfRscdOMxI1Mh8">Rebekah Gee on LinkedIn on Medicaid cuts</a></p><p><a href="https://www.kff.org/medicaid/issue-brief/5-key-facts-about-medicaid-work-requirements/">&#8220;5 Key Facts About Medicaid Work Requirements&#8221;</a></p><p><a href="https://www.kff.org/tracking-the-medicaid-provisions-in-the-2025-budget-bill/">&#8220;Health Provisions in the 2025 Federal Budget Reconciliation Bill&#8221;</a></p><p>A New COVID Booster Policy</p><p><a href="https://www.nejm.org/doi/full/10.1056/NEJMsb2506929">&#8220;An Evidence-Based Approach to Covid-19 Vaccination&#8221;</a></p><p><a href="https://www.statnews.com/2025/05/20/fda-vaccine-framework-new-covid-shot-recommendations-vinay-prasad-marty-makary/">&#8220;FDA will limit Covid vaccines to people over 65 or at high risk of serious illness, leaders say&#8221;</a></p><p><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/fda-sets-new-covid-booster-guidelines-requiring-trials-approvals-healthy-adults-2025-05-20/">&#8220;FDA tightens requirements for COVID vaccine, adding trials for healthy adults&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[James Dodington: Protecting Kids from Gun Violence]]></title><description><![CDATA[Howie and Harlan are joined by James Dodington, a Yale pediatric emergency medicine physician and an expert in community-based violence prevention. Harlan reports on the remarkable financial results and sometimes questionable science of Hims &...]]></description><link>https://neverdelegateunderstanding.substack.com/p/james-dodington-protecting-kids-from-143</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/james-dodington-protecting-kids-from-143</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 15 May 2025 13:44:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298523/f297d946ee9f9c179cba4293cad243bd.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by James Dodington, a Yale pediatric emergency medicine physician and an expert in community-based violence prevention. Harlan reports on the remarkable financial results and sometimes questionable science of Hims &amp; Hers Health; Howie discusses UnitedHealthcare&#8217;s faltering stock price in the face of anger over aggressive care denial and a lawsuit from shareholders.</p><p>Links:</p><p>Oscar Health and Hims &amp; Hers</p><p><a href="https://www.forbes.com/sites/brucejapsen/2025/05/07/oscar-health-profits-eclipse-275-million-as-obamacare-enrollment-soars/">&#8220;Oscar Health Profits Eclipse $275 Million As Obamacare Enrollment Soars&#8221;</a></p><p><a href="https://www.wsj.com/health/pharma/hims-hers-health-revenue-jumps-but-outlook-disappoints-a3dbdb6d">&#8220;Hims &amp; Hers Health Revenue Jumps, But Outlook Disappoints&#8221;</a></p><p><a href="https://www.fiercehealthcare.com/health-tech/hims-hers-q1-revenue-doubles-586m-boosted-growth-weight-loss-business">&#8220;Hims &amp; Hers' Q1 revenue doubles to $586M, boosted by growth in weight loss business&#8221;</a></p><p><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/hims-hers-partners-with-novo-nordisk-sell-wegovy-its-platform-2025-04-29/">&#8220;Novo Nordisk to sell Wegovy through telehealth firms to cash-paying US customers&#8221;</a></p><p><a href="https://www.wsj.com/health/pharma/telehealth-hims-hair-loss-finasteride-side-effects-0bc5992f">&#8220;They Wanted a Quick Fix for Hair Loss. Instead, These Young Men Got Sick.&#8221;</a></p><p><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/eu-drugs-regulator-confirms-suicidal-thoughts-side-effect-anti-hair-loss-drug-2025-05-08/">&#8220;EU drugs regulator confirms suicidal thoughts as side effect of hair loss drug&#8221;</a></p><p><a href="https://www.ema.europa.eu/en/news/measures-minimise-risk-suicidal-thoughts-finasteride-dutasteride-medicines">&#8220;Measures to minimise risk of suicidal thoughts with finasteride and dutasteride medicines&#8221;</a></p><p><a href="https://www.fda.gov/drugs/human-drug-compounding/fda-alerts-health-care-providers-compounders-and-consumers-potential-risks-associated-compounded">&#8220;FDA alerts health care providers, compounders and consumers of potential risks associated with compounded topical finasteride products&#8221;</a></p><p>James Dodington</p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/joseph-sakran-confronting-gun-violence">Health &amp; Veritas Episode 81: Joseph Sakran: Confronting Gun Violence</a></p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/megan-ranney-whats-next-for-public-health">Health &amp; Veritas Episode 77: Megan Ranney: What&#8217;s Next for Public Health?</a></p><p><a href="https://www.cnn.com/2024/09/07/health/guns-death-us-children-teens-dg">&#8220;Children and teens are more likely to die by guns than anything else&#8221;</a></p><p><a href="https://us.pagefreezer.com/en-US/wa/browse/0a7f82bb-be6e-448a-ae11-373d22c37842?find-by-timestamp=2025-01-02T05:49:59Z&amp;url=https:%2F%2Fwww.hhs.gov%2Fabout%2Fnews%2F2024%2F06%2F25%2Fus-surgeon-general-issues-advisory-public-health-crisis-firearm-violence-united-states.html&amp;timestamp=2025-01-02T07:03:02Z">&#8220;U.S. Surgeon General Issues Advisory on the Public Health Crisis of Firearm Violence in the United States&#8221;</a></p><p><a href="https://publichealth.jhu.edu/2024/guns-remain-leading-cause-of-death-for-children-and-teens">&#8220;New Report Highlights U.S. 2022 Gun-Related Deaths: Firearms Remain Leading Cause of Death for Children and Teens, and Disproportionately Affect People of Color&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/29967056/">James Dodington: &#8220;Rural Versus Urban Hospitalizations for Firearm Injuries in Children and Adolescents&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/36106466/">&#8220;Disparities in Pediatric Mental and Behavioral Health Conditions&#8221;</a></p><p><a href="https://ysph.yale.edu/about-school-of-public-health/communications-public-relations/publications/public-health-magazine/article/special-report-dean-megan-ranney-brings-a-public-health-approach-to-the-countrys-gun-violence-epidemic/">&#8220;Special Report: Dean Megan Ranney Brings a Public Health Approach to the Country&#8217;s Gun Violence Epidemic&#8221;</a></p><p><a href="https://medicine.yale.edu/news-article/gun-violence-is-a-public-health-crisisbut-hospital-based-invention-programs-can-help-break-the-cycle/">&#8220;Gun Violence Is a Public Health Crisis&#8212;But Hospital-based Intervention Programs Can Help Break the Cycle&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/38020854/">&#8220;Implementation of an emerging hospital-based violence intervention program: a multimethod study&#8221;</a></p><p><a href="https://wraparound.ucsf.edu/">UCSF Wraparound Project: The Public Health Model for Violence Prevention</a></p><p><a href="https://medicine.yale.edu/news-article/just-listen/">&#8220;Just Listen&#8221;</a></p><p><a href="https://ysph.yale.edu/public-health-research-and-practice/interdepartmental-foci/firearm-injury-prevention/">Firearm Injury Prevention at the Yale School of Public Health</a></p><p><a href="https://ysph.yale.edu/news-article/11-years-after-sandy-hook-a-new-path-toward-healing-and-hope/">&#8220;11 Years After Sandy Hook&#8212;A New Path Toward Healing and Hope&#8221;</a></p><p><a href="https://ysph.yale.edu/about-school-of-public-health/communications-public-relations/podcasts/shared-humanity/">Nelba M&#225;rquez-Greene&#8217;s Shared Humanity Podcast</a></p><p><a href="https://www.4-ct.org/programs/violence-intervention-and-prevention">4-CT:Violence Intervention and Prevention</a></p><p><a href="https://www.newhavenindependent.org/article/new_cash_pilot_targets_gun_violence">&#8220;Cash Pilot Targets Violence Victims&#8221;</a></p><p><a href="https://yaledailynews.com/blog/2024/10/13/how-unrestricted-cash-aid-is-transforming-violence-intervention-in-connecticut/">&#8220;How unrestricted cash aid is transforming violence intervention in Connecticut&#8221;</a></p><p><a href="https://medicine.yale.edu/news-article/gun-violence-is-a-public-health-crisisbut-hospital-based-invention-programs-can-help-break-the-cycle/">Pepe Vega&#8217;s story: &#8220;Gun Violence Is a Public Health Crisis&#8212;But Hospital-based Intervention Programs Can Help Break the Cycle"</a></p><p><a href="https://ysph.yale.edu/news-article/yale-undergraduate-team-takes-first-place-in-national-health-policy-competition/">&#8220;Yale undergraduate team takes first place in national health policy competition&#8221;</a></p><p>UnitedHealthcare</p><p><a href="https://www.wsj.com/health/healthcare/unitedhealth-names-new-ceo-suspends-2025-guidance-ed8244a1">&#8220;UnitedHealth CEO Is Out, Sending Shares Plummeting&#8221;</a></p><p><a href="https://www.nbcnews.com/business/business-news/unitedhealthcare-sued-shareholders-reaction-ceos-killing-rcna205550">&#8220;UnitedHealthcare sued by shareholders over reaction to CEO's killing&#8221;</a></p><p><a href="https://www.documentcloud.org/documents/25933445-show-temp-4/">UnitedHealth Shareholder Lawsuit</a></p><p><a href="https://www.reuters.com/sustainability/boards-policy-regulation/unitedhealths-string-setbacks-exec-murder-cyber-attack-2025-05-13/">&#8220;UnitedHealth's string of setbacks, from exec murder to cyber attack&#8221;</a></p><p><a href="https://www.bloomberg.com/news/articles/2025-05-09/zepbound-patients-fear-switch-to-wegovy-after-cvs-deal">&#8220;Zepbound Patients Fear Losing Coverage After CVS Deal for Wegovy&#8221;</a></p><p><a href="https://www.nbcnews.com/health/health-news/zepbound-beats-wegovy-weight-loss-first-head-head-trial-blockbuster-dr-rcna206162">&#8220;Zepbound beats Wegovy for weight loss in first head-to-head trial of blockbuster drugs&#8221;</a></p>]]></content:encoded></item><item><title><![CDATA[Thomas Gill: The Secrets to an Active Old Age]]></title><description><![CDATA[Howie and Harlan are joined by Thomas Gill, a Yale geriatrician whose research tracks the factors that contribute to disability in older adults&#8212;and those that support continued independence. And they discuss the contrarian tapped to evaluate...]]></description><link>https://neverdelegateunderstanding.substack.com/p/thomas-gill-the-secrets-to-an-active-5f3</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/thomas-gill-the-secrets-to-an-active-5f3</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 08 May 2025 14:11:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298524/6d91c7f01b81b82b1d9bf81c479368b4.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by Thomas Gill, a Yale geriatrician whose research tracks the factors that contribute to disability in older adults&#8212;and those that support continued independence. And they discuss the contrarian tapped to evaluate vaccines at the FDA, allegations of kickbacks against insurers, and the potential end of a loophole that has allowed states to collect additional Medicaid funding.&nbsp;</p><p>Links:</p><p>Vinay Prasad at the FDA</p><p><a href="https://www.statnews.com/2025/05/06/vinay-prasad-fda-center-for-biologics-evaluation-and-research-peter-marks-hhs-rfk-jr-makary/">&#8220;Vinay Prasad tapped to run FDA center that regulates vaccines, gene therapies&#8221;</a></p><p><a href="https://www.statnews.com/2025/05/06/vinay-prasad-fda-vaccine-regulator-analysis-of-previous-contrarian-comments-covid-autism-mmr-shots/">&#8220;Vinay Prasad, in his own words, outlines the philosophy he&#8217;ll bring to the FDA&#8221;</a></p><p><a href="https://www.statnews.com/2025/03/28/fda-peter-marks-cber-director-resigns-rfk-jr/">&#8220;Peter Marks, FDA&#8217;s top vaccine regulator, forced out&#8221;</a></p><p><a href="https://www.linkedin.com/feed/update/urn:li:activity:7325575702433439744/">Howard Forman on LinkedIn on Vinay Prasad's Appointment</a></p><p><a href="https://www.drvinayprasad.com/">Vinay Prasad's Substack</a></p><p>Insurance News</p><p><a href="https://www.wsj.com/health/healthcare/doj-files-complaint-against-aetna-ehealth-others-alleging-medicare-advantage-kickbacks-62487269">&#8220;Justice Department Sues Big Medicare Insurers Alleging Kickbacks&#8221;</a></p><p><a href="https://www.fiercehealthcare.com/payers/aetna-exit-aca-exchanges-2026">&#8220;Aetna to exit the ACA exchanges in 2026&#8221;</a></p><p><a href="https://www.modernhealthcare.com/insurance/aetna-exchange-aca-market-exit">&#8220;What Aetna quitting the exchanges says about the exchanges&#8221;</a></p><p><a href="https://www.cnbc.com/2025/05/01/cvs-wegovy-caremark-patients.html">&#8221;CVS to boost access to Novo Nordisk&#8217;s weight loss treatment Wegovy for patients on its drug plans&#8221;</a></p><p>Thomas Gill</p><p><a href="https://www.statista.com/statistics/457822/share-of-old-age-population-in-the-total-us-population/">Statista: Share of old age population (65 years and older) in the total U.S. population from 1950 to 2050</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/25387728/">Thomas Gill: &#8220;A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/12362007/">Thomas Gill: &#8220;A Program to Prevent Functional Decline in Physically Frail, Elderly Persons Who Live at Home&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/37052919/">&#8220;Prehabilitation for Patients Undergoing Orthopedic Surgery: A Systematic Review and Meta-analysis&#8221;</a></p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6430278/#:~:text=Allostatic%20load%20is%20a%20physiological,poor%20health%20and%20maladaptive%20trajectories">&#8220;Allostatic Load: Importance, Markers, and Score Determination in Minority and Disparity Populations&#8221;</a></p><p><a href="https://www.sciencedirect.com/science/article/pii/S1279770723013210?via%3Dihub">&#8220;Cohort Profile: The Precipitating Events Project (PEP Study)&#8221;</a></p><p><a href="https://news.yale.edu/2001/10/30/memoriam-yale-expert-clinical-research-methods-alvan-r-feinstein">&#8220;In Memoriam: Yale Expert in Clinical Research Methods, Alvan R. Feinstein&#8221;</a></p><p>Medicaid Cuts</p><p><a href="https://www.kff.org/medicaid/issue-brief/putting-880-billion-in-potential-federal-medicaid-cuts-in-context-of-state-budgets-and-coverage/">&#8220;Putting $880 Billion in Potential Federal Medicaid Cuts in Context of State Budgets and Coverage&#8221;</a></p><p><a href="https://www.statnews.com/2025/05/07/medicaid-eligibility-draws-attention-of-republicans-looking-for-cuts/">&#8220;Republicans are running out of ways to cut Medicaid as moderates and hard-liners clash&#8221;</a></p><p><a href="https://www.nytimes.com/2025/05/06/upshot/medicaid-hospitals-republicans-cuts.html">&#8220;G.O.P. Targets a Medicaid Loophole Used by 49 States to Grab Federal Money&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Joel Bervell: The Healthcare Communicator]]></title><description><![CDATA[Howie and Harlan are joined by Joel Bervell, a recent medical school graduate who uses social media platforms to combat misinformation and explain racial biases in healthcare. Harlan discusses his new Wall Street Journal commentary highlighting the...]]></description><link>https://neverdelegateunderstanding.substack.com/p/joel-bervell-the-healthcare-communicator-db0</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/joel-bervell-the-healthcare-communicator-db0</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 01 May 2025 17:15:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298525/36a997c05cea64bafd793e0ca939f453.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by Joel Bervell, a recent medical school graduate who uses social media platforms to combat misinformation and explain racial biases in healthcare. Harlan discusses his new <em>Wall Street Journal</em> commentary highlighting the link between viral infections and chronic diseases; Howie reports on powerful new evidence for the effectiveness of the HPV vaccine and warns of the dangers of a vaccine-skeptical presidential administration.</p><p>Links:</p><p>Viral Infection and Chronic Disease</p><p><a href="https://www.wsj.com/opinion/how-to-lead-a-chronic-disease-revolution-research-covid-infection-congress-d304d2ac">Harlan Krumholz: &#8220;How to Lead a Chronic Disease Revolution&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/40175543/">&#8220;A natural experiment on the effect of herpes zoster vaccination on dementia&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/35585196/">&#8220;Unexplained post-acute infection syndromes&#8221;</a></p><p>Joel Bervell</p><p><a href="https://joelbervell.com/#homepage">Joel Bervell</a></p><p><a href="https://www.tiktok.com/@joelbervell?lang=en">Joel Bervell on TikTok</a></p><p><a href="https://www.instagram.com/joelbervell/?hl=en">Joel Bervell on Instagram</a></p><p><a href="https://www.youtube.com/watch?v=v2-cS-Qrzzg">&#8220;TikTok's 'Medical Mythbuster' Helps Save Lives By Tackling Racial &amp; Gender Disparities In Healthcare&#8221;</a></p><p><a href="https://whyy.org/segments/how-the-pulse-oximeter-became-infamous-on-tiktok/">&#8220;How the pulse oximeter became infamous on TikTok&#8221;</a></p><p><a href="https://www.nejm.org/doi/full/10.1056/nejmc2029240">&#8220;Racial Bias in Pulse Oximetry Measurement&#8221;</a></p><p><a href="https://www.tiktok.com/@joelbervell/video/6911512883595726086?_r=1&amp;_t=8b8yUYCfGgA">Joel Bervell&#8217;s TikTok on the pulse oximeter</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/38418440/">Joel Bervell: &#8220;The eGFR Equation&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/36069880/">&#8220;Race Correction and the X-Ray Machine: The Controversy over Increased Radiation Doses for Black Americans in 1968&#8221;</a></p><p><a href="https://www.instagram.com/joelbervell/reel/DHmgTAsy-nZ/">Joel Bervell: &#8220;For over 50 years, X-ray technicians were taught to administer higher radiation doses to Black patients&#8221;</a></p><p><a href="https://www.instagram.com/reel/C4l-Tz0PtXh/">Joel Bervell&#8217;s Instagram reel on bias in the measurement of lung capacity</a></p><p><em><a href="https://heathbrothers.com/books/made-to-stick/">Made to Stick: Why Some Ideas Survive and Others Die</a></em></p><p><a href="https://www.linkedin.com/in/joelbervell/">Joel Bervell on LinkedIn</a></p><p><a href="https://www.youtube.com/@TheDoctorIsInShow">Joel Bervell on YouTube: The Doctor Is In</a></p><p><a href="https://www.kickstarter.com/projects/thedoctorisintvshow/the-doctor-is-in">Kickstarter: The Doctor Is In</a></p><p><a href="https://www.ama-assn.org/delivering-care/health-equity/medical-mythbuster-joel-bervell-md-how-teach-kids-about-medicine-and">&#8220;Medical mythbuster Joel Bervell, MD, on how to teach kids about medicine and address misinformation&#8221;</a></p><p><a href="https://my.clevelandclinic.org/health/diseases/23398-amyloidosis">Cleveland Clinic: Amyloidosis</a></p><p><a href="https://www.instagram.com/joelbervell/reel/Ci1Igk-j1wy/">Joel Bervel&#8217;s Instagram reel on the GFR equation</a></p><p><a href="https://medicine.yale.edu/news-article/abandoning-a-race-biased-tool-for-kidney-diagnosis/">&#8220;Abandoning a Race-biased Tool for Kidney Diagnosis&#8221;</a></p><p><a href="https://optn.transplant.hrsa.gov/news/optn-board-approves-elimination-of-race-based-calculation-for-transplant-candidate-listing/">&#8220;OPTN Board approves elimination of race-based calculation for transplant candidate listing&#8221;</a></p><p><a href="https://www.pewresearch.org/journalism/2024/11/18/americas-news-influencers/">&#8220;America&#8217;s News Influencers&#8221;</a></p><p><a href="https://peabodyawards.com/stories/nominees-announced-entertainment-kids-arts/">&#8220;85th Annual Peabody Awards Announce Nominees for the Arts, Children&#8217;s/Youth, Entertainment, and Interactive &amp; Immersive Categories</a></p><p>Vaccines and the Federal Healthcare Agencies</p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/aging-in-bursts-and-other-news">Health &amp; Veritas Episode 165: &#8220;Aging in Bursts and Other News&#8221;</a></p><p><a href="https://www.statnews.com/2025/04/28/hpv-vaccine-single-dose-prevents-infection-just-as-well-as-two-doses-hci-clinical-trial/">&#8220;U.S. government researchers present &#8216;phenomenal&#8217; new data on HPV vaccines&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/38247547/">&#8220;Invasive cervical cancer incidence following bivalent human papillomavirus vaccination: a population-based observational study of age at immunization, dose, and deprivation&#8221;</a></p><p><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/kennedy-played-key-role-vaccine-case-against-merck-2025-01-18/">&#8220;Kennedy played key role in Gardasil vaccine case against Merck&#8221;</a></p><p><a href="https://www.statnews.com/2025/04/10/rfk-jr-measles-vaccines-outbreak-comments/">&#8220;RFK Jr. suggests some vaccines are risky or ineffective, downplays measles threat&#8221;</a></p><p><a href="https://www.cbsnews.com/news/fda-covid-booster-shots-marty-makary/">&#8220;FDA chief says they're looking at whether to approve COVID shots for next winter&#8221;</a></p><p><a href="https://www.statnews.com/2025/04/29/fda-vaccine-criticism-seeping-into-official-policy-rfk-jr-marty-makary/">&#8220;How Marty Makary&#8217;s FDA is embracing a more skeptical view of vaccines&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Afib, AI Agents, and Other News]]></title><description><![CDATA[Howie reflects on his decades-long experience with paroxysmal atrial fibrillation and the procedure that has changed his life. Howie and Harlan report on healthcare issues in the news, including the measles outbreak and a vision for a team of personal...]]></description><link>https://neverdelegateunderstanding.substack.com/p/afib-ai-agents-and-other-news-d22</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/afib-ai-agents-and-other-news-d22</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 24 Apr 2025 13:47:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298526/c9be8134815a444feacd10d4bae1ba26.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie reflects on his decades-long experience with paroxysmal atrial fibrillation and the procedure that has changed his life. Howie and Harlan report on healthcare issues in the news, including the measles outbreak and a vision for a team of personal healthcare AI agents. And student research assistants In&#232;s Gilles and Sophia Stumpf visit for a farewell interview.</p><p>Links:</p><p><a href="https://erictopol.substack.com/">Eric Topol: Ground Truths</a></p><p><a href="https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666">Eric Topol: </a><em><a href="https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666">Super Agers</a></em></p><p><a href="https://www.amazon.com/Expert-Guide-Beating-Heart-Disease-ebook/dp/B000FCJZ2M/ref=sr_1_8">Harlan Krumholz: </a><em><a href="https://www.amazon.com/Expert-Guide-Beating-Heart-Disease-ebook/dp/B000FCJZ2M/ref=sr_1_8">The Expert Guide to Beating Heart Disease: What You Absolutely Must Know</a></em></p><p>Paroxysmal Atrial Fibrillation</p><p><a href="https://www.medicalnewstoday.com/articles/316281">&#8220;What to know about paroxysmal atrial fibrillation&#8221;</a></p><p><a href="https://medicine.yale.edu/profile/joseph-akar/">Joseph Akar, MD, PhD</a></p><p><a href="https://www.mayoclinic.org/tests-procedures/atrial-fibrillation-ablation/about/pac-20384969#:~:text=Atrial%20fibrillation%20ablation%20is%20a,t%20pass%20through%20scar%20tissue.">Mayo Clinic: Atrial fibrillation ablation</a></p><p><a href="https://www.resolvemedicalbills.com/blog/the-true-cost-of-a-cardiac-ablation-in-the-us">&#8220;The True Cost of a Cardiac Ablation in the U.S.&#8221;</a></p><p>AI Agents</p><p><a href="https://www.linkedin.com/pulse/four-ai-agents-your-health-carl-bradford-byers--pg3nf/">&#8220;The Four AI Agents of Your Health&#8221;</a></p><p><a href="https://www.nytimes.com/2025/04/03/technology/ai-futures-project-ai-2027.html">&#8220;This A.I. Forecast Predicts Storms Ahead&#8221;</a></p><p>Measles</p><p><a href="https://www.cdc.gov/measles/data-research/index.html">CDC: Measles Cases and Outbreaks</a></p><p><a href="https://www.nytimes.com/2025/04/22/health/measles-southwest-outbreak.html">&#8220;Measles Surge in Southwest Is Now the Largest Single Outbreak Since 2000&#8221;</a></p><p><a href="https://www.mayoclinic.org/diseases-conditions/history-disease-outbreaks-vaccine-timeline/measles">Mayo Clinic: History of Measles</a></p><p>Food as Medicine</p><p><a href="https://bmcmededuc.biomedcentral.com/articles/10.1186/s12909-025-07103-z">&#8220;Cooking with the curriculum: a pilot culinary medicine program at the Larner College of Medicine&#8221;</a></p><p><a href="https://medicine.yale.edu/news-article/bringing-culinary-medicine-to-yales-new-teaching-kitchen/">&#8220;Bringing Culinary Medicine to Yale&#8217;s New Teaching Kitchen&#8221;</a></p><p>Bird Flu</p><p><a href="https://www.cdc.gov/bird-flu/situation-summary/index.html">CDC: H5 Bird Flu: Current Situation</a></p><p><a href="https://www.cidrap.umn.edu/avian-influenza-bird-flu/vietnam-reports-h5n1-avian-flu-case-encephalitis#:~:text=Health%20officials%20in%20Vietnam%20have,first%20human%20case%20of%202025.">&#8220;Vietnam reports H5N1 avian flu case with encephalitis&#8221;</a></p><p>Exercise and Brain Waste</p><p><a href="https://www.nature.com/articles/s41467-025-58726-1">&#8220;Long-term physical exercise facilitates putative glymphatic and meningeal lymphatic vessel flow in humans&#8221;</a></p><p><a href="https://www.npr.org/sections/shots-health-news/2024/06/26/g-s1-6177/brain-waste-removal-system-amyloid-alzheimer-toxins#:~:text=From%20mice%20to%20humans,eventually%20out%20of%20the%20body">&#8220;The brain makes a lot of waste. Now scientists think they know where it goes&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Deepak D’Souza: Perils of Cannabis and Promise of Psychedelics]]></title><description><![CDATA[Deepak D'Souza, the Vikram Sodhi &#8217;92 Professor of Psychiatry at Yale, explains risks from highly potent cannabinoids and research on treating mental health conditions with psychedelics. Harlan reports on efforts to understand the neuroscience around...]]></description><link>https://neverdelegateunderstanding.substack.com/p/deepak-dsouza-perils-of-cannabis-423</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/deepak-dsouza-perils-of-cannabis-423</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 17 Apr 2025 13:01:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298527/3b3e7e352e82621e01744767d521f892.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Deepak D'Souza, the Vikram Sodhi &#8217;92 Professor of Psychiatry at Yale, explains risks from highly potent cannabinoids and research on treating mental health conditions with psychedelics. Harlan reports on efforts to understand the neuroscience around artificial sweeteners. Howie highlights insights from a physician pay survey.</p><p>Links:</p><p>Artificial Sweeteners</p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.who.int%2Fnews%2Fitem%2F15-05-2023-who-advises-not-to-use-non-sugar-sweeteners-for-weight-control-in-newly-released-guideline&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111296514%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=CpuTANZq4BnnmbtvFLjKZgqEwdkQK12B8cA9JAYOMdg%3D&amp;reserved=0">"WHO advises not to use non-sugar sweeteners for weight control in newly released guideline"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F40140714%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111305892%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=F%2Bd8n1J5%2BISm9lEvf1KUZ1eXTz%2FOZM2qsRbq9ir7au4%3D&amp;reserved=0">"Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.cnn.com%2F2025%2F03%2F29%2Fhealth%2Fartificial-sweetener-sucralose-hunger-signals-wellness%2Findex.html&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111315280%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=EUPjXwJ%2FL%2FaVvff1ZEEpLpnLSt9yX%2FHh7q2pSdCvPEQ%3D&amp;reserved=0">"Artificial sweetener found in diet drinks linked to brain changes that increase appetite, study finds"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.wsj.com%2Farticles%2Fwhy-one-cardiologist-has-drunk-his-last-diet-soda-1505398755&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111323876%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=2AQv5Xo6sOM%2BkXlv2mTI4A2kH%2FMquIY8B9J2A3gRdF4%3D&amp;reserved=0">"Why One Cardiologist Has Drunk His Last Diet Soda"</a></p><p>Cannabis</p><p><a href="https://medicine.yale.edu/news-article/not-your-grandmothers-marijuana-rising-thc-concentrations-in-cannabis-can-pose-devastating-health-risks/">"Marijuana: Rising THC Concentrations in Cannabis Can Pose Health Risks"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.frontiersin.org%2Fjournals%2Fpsychiatry%2Farticles%2F10.3389%2Ffpsyt.2021.689444%2Ffull&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111332778%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=YjDxYysd2UQNXmnRhl4nRgQaKyKEV3m7o0gOb9g0M7o%3D&amp;reserved=0">"Cannabis and Driving"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.webmd.com%2Fpain-management%2Fcbd-thc-difference&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111341798%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=ntX7RMYDvY%2FhuXTyL9Cx7opMCIAX1%2BC5R9YHUnO7Bhg%3D&amp;reserved=0">"CBD vs. THC: What's the Difference?"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nature.com%2Farticles%2F1300496&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111350559%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=C3xM0kO2zt8eTMDVjWjhKybkVadlAek3fCtjnhQZuUw%3D&amp;reserved=0">"The Psychotomimetic Effects of Intravenous Delta-9-Tetrahydrocannabinol in Healthy Individuals: Implications for Psychosis"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F26858993%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111359284%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=ayfBdbhm%2B%2BaTkHuYm1G1nyHVGxZK0N75SWlNkYie6p4%3D&amp;reserved=0">"Rapid Changes in CB1 Receptor Availability in Cannabis Dependent Males after Abstinence from Cannabis"</a></p><p><a href="https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476">"Cannabidiol (CBD): What we know and what we don't"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.fda.gov%2Fnews-events%2Fpress-announcements%2Ffda-approves-first-drug-comprised-active-ingredient-derived-marijuana-treat-rare-severe-forms&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111377074%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=j8ElPN8X%2B8ReeaW8MjflfkWXnBVli7Ix8cRZdPXdWv4%3D&amp;reserved=0">"FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpsychiatryonline.org%2Fdoi%2F10.1176%2Fappi.ajp.162.3.458&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111386165%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=T0p1JnK5XC8X7gl81g2q7JWkM1yR5ksqzYX%2F9o7LE2g%3D&amp;reserved=0">"Jacques Joseph Moreau (1804&#8211;1884)"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F31131781%2F%23%3A~%3Atext%3DResults%253A%2520In%25201892%252C%2520heavy%2520cannabis%2Cfamily%2520history%2520of%2520mental%2520illness&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111396134%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=6vU2%2FiLuPjoDcLr7Quk2rP7chtvScw%2FtR9Diqk5UaWk%3D&amp;reserved=0">"Cannabis and psychosis: revisiting a nineteenth century study of 'Indian Hemp and Insanity' in Colonial British India"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fpii%2FS0006322304013101&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111405708%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=7Xl7BjAqlHzLUhkE%2F79KurJAU37jPk4QBoh96vsTQFU%3D&amp;reserved=0">"Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F30902669%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111415038%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=zt79VHB1rll2LGnOLCgKzwldIV9KNdWwXfhFeBwnrl4%3D&amp;reserved=0">"The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F34132750%2F&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111424176%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=MZ4e1NYPt6GBfuoGbKgwakuGVr7HLtHUE%2B13ld4EJ%2B0%3D&amp;reserved=0">"Association of Cannabis Use During Adolescence With Neurodevelopment"</a></p><p><a href="https://www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569">"The endocannabinoid system: Essential and mysterious"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmedlineplus.gov%2Fdruginfo%2Fmeds%2Fa607054.html&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111433909%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=I7GiQkQ0JUjPzz%2By95DRIGhaiLxhx6hHhRh%2B40921ew%3D&amp;reserved=0">Dronabinol: MedlinePlus</a></p><p>Dr. D&#8217;Souza</p><p><a href="https://news.yale.edu/2024/06/04/dsouza-named-vikram-sodhi-professor-psychiatry">"D&#8217;Souza named Vikram Sodhi Professor of Psychiatry"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.ctinsider.com%2Fconnecticut%2Farticle%2Fct-ayahuasca-dmt-psilocybin-yale-depression-19579193.php&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111447518%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=KfQyjumdqCb1ZNXT2wlofT4jsK82oj5Wm6J8LEcf7cI%3D&amp;reserved=0">"CT Yale researcher gets $3 million chair to study DMT use for depression, PTSD"</a></p><p>Physician Pay</p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.medscape.com%2Fslideshow%2F2025-compensation-overview-6018103&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111457354%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=dAxYC%2FDaaA9uulCY7eApGV0jrRHXwXPFFldWzmRTFVA%3D&amp;reserved=0">"Comparing Your Pay Against Your Peers&#8217;: Medscape Physician Compensation Report 2025"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.fiercehealthcare.com%2Fproviders%2Fphysician-compensation-rose-36-2024-not-all-specialties-got-raise&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111466974%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=1U%2FhPZDrdsf8Zj%2BPZ%2BTV7ri3mZj7aHSCdxH59qcd6vI%3D&amp;reserved=0">"Physician compensation rose 3.6% in 2024, but not all specialties got a raise"</a></p><p><a href="https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.ama-assn.org%2Fmedical-students%2Fpreparing-residency%2Fbiggest-match-day-ever-here-s-what-2025-numbers-reveal&amp;data=05%7C02%7Cted.ocallahan%40yale.edu%7Cad5d756d431642e803ab08dd7d40404c%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C638804437111476580%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=iX4fAJxNNRbZQqz7AdFiE0CL3IxnZ%2FopCF7dJLa2BZM%3D&amp;reserved=0">"Biggest Match Day ever: Here&#8217;s what the 2025 numbers reveal"</a></p><p><a href="https://som.yale.edu/podcasts/health-veritas/ryan-schwarz-thinking-differently-about-primary-care-crisis-167">"Ryan Schwarz: Thinking Differently about the Primary Care Crisis"</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>. <a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Evan Sussman: Expanding Access to Fertility Drugs]]></title><description><![CDATA[Howie and Harlan welcome Evan Sussman, the CEO of Granata Bio, which aims to bring IVF and fertility drugs that have been proven in other markets to the United States. Harlan reports on Elon Musk&#8217;s Neuralink, which will test a technology to restore...]]></description><link>https://neverdelegateunderstanding.substack.com/p/evan-sussman-expanding-access-to-171</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/evan-sussman-expanding-access-to-171</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 10 Apr 2025 13:21:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298528/f8ae7576d8d6690b7cb79df5eff07d61.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan welcome Evan Sussman, the CEO of Granata Bio, which aims to bring IVF and fertility drugs that have been proven in other markets to the United States. Harlan reports on Elon Musk&#8217;s Neuralink, which will test a technology to restore rudimentary sight to the blind; Howie tries to reconcile conflicting reports about the viability of the Medicare trust fund.&nbsp;</p><p>Links:</p><p>Neuralink</p><p><a href="https://www.mobihealthnews.com/news/elon-musk-announces-neuralink-s-first-human-implant-blindsight-coming-year">&#8220;Elon Musk announces Neuralink&#8217;s first human implant of Blindsight coming this year&#8221;</a></p><p><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/musks-neuralink-receives-fdas-breakthrough-device-tag-brain-implant-2024-09-17/">&#8220;Musk's Neuralink gets FDA's breakthrough device tag for 'Blindsight' implant&#8221;</a></p><p><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/elon-musks-neuralink-receives-canadian-approval-brain-chip-trial-2024-11-21/">&#8220;Elon Musk's Neuralink receives Canadian approval for brain chip trial&#8221;</a></p><p><a href="https://www.forbes.com/profile/elon-musk/">Forbes: Elon Musk</a></p><p>Granata Bio</p><p><a href="https://www.granata.bio/">Granata Bio</a></p><p>&#8202;<a href="https://www.cbsnews.com/news/ivf-fertility-treatment-costs-insurance-coverage-medicaid/">&#8220;Fertility treatment costs are out of reach for many Americans, even with insurance&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/23905708/">&#8220;Acceptable cost for the patient and society&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/37665313/#full-view-affiliation-22">&#8220;Meeting the demand for fertility services: the present and future of reproductive endocrinology and infertility in the United States&#8221;</a></p><p><a href="https://resolve.org/learn/financial-resources/insurance-coverage/insurance-coverage-by-state/">RESOLVE: The National Infertility Association: Insurance Coverage by State</a></p><p><a href="https://www.npr.org/2024/10/10/nx-s1-5147815/ivf-insurance-coverage-employers">&#8220;Politicians say health plans should cover IVF. Currently only 1 in 4 employers do&#8221;</a></p><p><a href="https://som.yale.edu/blog/catching-up-with-alumni-the-founders-of-granata-bio">&#8220;Catching Up with Alumni: The Founders of Granata Bio&#8221;</a></p><p><a href="https://www.prnewswire.com/news-releases/ibsa-group-and-granata-bio-announces-first-patient-screened-in-pivotal-progress-clinical-trial-of-progesterone-ibsa-301652741.html">&#8220;IBSA Group and Granata Bio announces first patient screened in pivotal PROGRESS clinical trial of Progesterone-IBSA&#8221;</a></p><p><a href="https://www.prnewswire.com/news-releases/womens-health-innovator-granata-bio-raises-14m-series-a-led-by-gv-to-accelerate-fertility-biopharma-pipeline-302034754.html">&#8220;Women's Health Innovator Granata Bio Raises $14M Series A led by GV to Accelerate Fertility Biopharma Pipeline&#8221;</a></p><p><a href="https://www.prnewswire.com/news-releases/womens-health-innovator-granata-bio-raises-15m-series-a-to-further-develop-and-expand-reproductive-health-pipeline-302350977.html">&#8220;Women's Health Innovator Granata Bio Raises $15M Series A+ to Further Develop and Expand Reproductive Health Pipeline&#8221;</a></p><p><a href="https://www.reuters.com/business/healthcare-pharmaceuticals/trump-signs-executive-order-expanding-access-ivf-white-house-says-2025-02-18/">&#8220;Trump signs executive order seeking to expand IVF access&#8221;</a></p><p>The Medicare Trust Fund</p><p><a href="https://www.cbo.gov/publication/61187">&#8220;The Long-Term Budget Outlook: 2025 to 2055&#8221;</a></p><p><a href="https://www.statnews.com/2025/04/05/medicare-hospital-insurance-trust-fund-cbo-estimate-2052/">&#8220;Medicare gets a big (unofficial) surprise: a 17-year extension on when it&#8217;ll run dry&#8221;</a></p><p><a href="https://www.cms.gov/newsroom/press-releases/cms-finalizes-2026-payment-policy-updates-medicare-advantage-and-part-d-programs">&#8220;CMS Finalizes 2026 Payment Policy Updates for Medicare Advantage and Part D Programs&#8221;</a>&nbsp;</p><p><a href="https://www.wsj.com/health/healthcare/private-medicare-plans-to-get-big-payment-boost-from-trump-administration-017d9aaa">&#8220;Health Insurer Stocks Soar on Medicare Rate Boost&#8221;</a></p><p><a href="https://www.acpjournals.org/doi/10.7326/ANNALS-24-01345">&#8220;Insurer-Level Estimates of Revenue From Differential Coding in Medicare Advantage&#8221;</a></p><p><a href="https://www.medicare.gov/about-us/how-is-medicare-funded">Medicare.gov: &#8220;How is Medicare funded?&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Alexi Nazem: Building Healthcare Solutions]]></title><description><![CDATA[Howie and Harlan are joined by Alexi Nazem, a Yale-trained internist who co-founded the healthcare staffing company Nomad Health and now leads healthcare investments at AlleyCorp. Harlan reports on new research from the American College of Cardiology...]]></description><link>https://neverdelegateunderstanding.substack.com/p/alexi-nazem-building-healthcare-solutions-5ca</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/alexi-nazem-building-healthcare-solutions-5ca</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 03 Apr 2025 13:41:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298529/12aa2f59c30d20005b75e575fd62f8c2.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by Alexi Nazem, a Yale-trained internist who co-founded the healthcare staffing company Nomad Health and now leads healthcare investments at AlleyCorp. Harlan reports on new research from the American College of Cardiology meeting; Howie examines the consequences of vast staffing cuts in the federal healthcare infrastructure.&nbsp;</p><p>Links:</p><p>Research from the American College of Cardiology Meeting</p><p><a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00509-4/fulltext">&#8220;Semaglutide and walking capacity in people with symptomatic peripheral artery disease and type 2 diabetes (STRIDE): a phase 3b, double-blind, randomised, placebo-controlled trial&#8221;</a></p><p><a href="https://www.jacc.org/doi/10.1016/j.jacc.2025.03.003">&#8220;Early Intra-Aortic Balloon Support for Heart Failure-Related Cardiogenic Shock: A Randomized Clinical Trial&#8221;</a></p><p><a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2416112">&#8220;Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism&#8221;</a></p><p>Alexi Nazem</p><p><a href="https://www.genome.gov/human-genome-project">The Human Genome Project</a></p><p><a href="https://www.ihi.org/">Institute for Healthcare Improvement</a></p><p><a href="https://www.ihi.org/insights/100000-lives-campaign-ten-years-later">&#8220;100,000 Lives Campaign: Ten Years Later&#8221;</a></p><p><a href="https://www.nejm.org/doi/full/10.1056/NEJM198901053200110">&#8220;Continuous Improvement as an Ideal in Health Care&#8221;</a></p><p><a href="https://jamanetwork.com/journals/jama/fullarticle/181589">&#8220;The Science of Improvement&#8221;</a></p><p><a href="https://insights.som.yale.edu/podcasts/health-veritas/max-laurans-an-entrepreneurial-life-in-medicine">Health &amp; Veritas Episode 145: Max Laurans: An Entrepreneurial Life in Medicine</a></p><p><a href="https://nomadhealth.com/about">Nomad Health</a></p><p><a href="https://cases.som.yale.edu/nomad-health-disruption-physician-staffing-services">Yale School of Management case study: &#8220;Nomad Health: The disruption of physician staffing services"</a></p><p><a href="https://www.forbes.com/sites/katiejennings/2022/06/27/staffing-marketplace-nomad-health-raises-105-million-as-it-expands-beyond-travel-nurses/">&#8220;Staffing Marketplace Nomad Health Raises $105 Million As It Expands Beyond Travel Nurses&#8221;</a></p><p><a href="https://www.newyorker.com/science/medical-dispatch/america-is-running-out-of-nurses">&#8220;America Is Running Out of Nurses&#8221;</a></p><p><a href="https://www.forbes.com/sites/katiejennings/2023/02/09/staffing-marketplace-nomad-health-lays-off-20-of-workforce-employees-say/">&#8220;Staffing Marketplace Nomad Health Lays Off 17% Of Workforce&#8221;</a></p><p><a href="https://www.businessinsider.com/ai-deals-growing-faster-healthcare-tech-svb-venture-capital-2024-6">&#8220;Why AI deals in healthcare have grown faster than other areas of tech &#8212; and what VCs are paying close attention to&#8221;</a></p><p>Turmoil at Federal Health Agencies</p><p><a href="https://www.nytimes.com/2025/04/01/us/politics/trump-federal-layoffs-health-food.html">&#8220;Mass Layoffs Hit Health Agencies That Track Disease and Regulate Food&#8221;</a></p><p><a href="https://www.npr.org/sections/shots-health-news/2025/03/28/nx-s1-5344010/fda-peter-marks-rfk-jr">&#8220;The top FDA vaccine official is forced out, cites RFK Jr.'s 'misinformation and lies'&#8220;</a></p><p><a href="https://www.statnews.com/2025/03/25/nih-cuts-include-hiv-aids-prevention-program-for-adolescents/">&#8220;NIH cuts halt 24-year program to prevent HIV/AIDS in adolescents and young adults&#8221;</a></p><p><a href="https://www.reuters.com/world/us/princeton-says-us-grants-frozen-follows-trump-administration-moves-against-other-2025-04-01/">&#8220;Princeton's US grants frozen, follows Trump actions against other schools&#8221;</a></p><p><a href="https://www.nytimes.com/2025/03/26/health/trump-state-health-grants-cuts.html">&#8220;Trump Administration Abruptly Cuts Billions From State Health Services&#8221;</a></p><p><a href="https://www.theguardian.com/us-news/2025/feb/22/texas-measles-outbreak">&#8220;Texas measles outbreak grows to 90 cases, worst level in 30 years&#8221;</a></p><p><a href="https://www.washingtonpost.com/nation/2025/02/22/trump-lawsuits-democratic-attorney-generals/">&#8220;As Trump pursues his policies, Democratic states block his path&#8221;</a></p><p><a href="https://www.cbsnews.com/news/foreign-aid-cuts-hiv-aids-deaths-study/">&#8220;Proposed foreign aid cuts could lead to millions of HIV deaths, study estimates&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Ryan Schwarz: Thinking Differently about the Primary Care Crisis]]></title><description><![CDATA[Howie and Harlan are joined by Ryan Schwarz, a Yale-trained MD-MBA who oversees accountable care for the Massachusetts Medicaid program, to discuss new models for addressing the severe shortage of primary care doctors in the U.S. Harlan looks at the...]]></description><link>https://neverdelegateunderstanding.substack.com/p/ryan-schwarz-thinking-differently-ed1</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/ryan-schwarz-thinking-differently-ed1</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 27 Mar 2025 14:10:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298530/128b1424f5e295316e1193ed6e94b968.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by Ryan Schwarz, a Yale-trained MD-MBA who oversees accountable care for the Massachusetts Medicaid program, to discuss new models for addressing the severe shortage of primary care doctors in the U.S. Harlan looks at the fallout from the bankruptcy of 23andMe; Howie reports on Match Day at Yale and medical schools around the country.</p><p>Links:</p><p>New Leadership</p><p><a href="https://www.nytimes.com/2025/03/25/health/trump-nih-fda-bhattacharya.html">&#8220;Senate Confirms Bhattacharya and Makary to H.H.S. Posts&#8221;</a></p><p><a href="https://www.nytimes.com/2025/03/13/world/europe/keir-starmer-nhs-england.html">&#8220;Keir Starmer Wants to Abolish N.H.S. England: What to Know About His Plan&#8221;</a></p><p>23andMe</p><p><a href="https://www.nytimes.com/2025/03/24/business/23andme-bankruptcy.html">&#8220;23andMe Files for Bankruptcy Amid Concerns About Security of Customers&#8217; Genetic Data&#8221;</a></p><p><a href="https://www.nytimes.com/2023/12/04/us/23andme-hack-data.html">&#8220;Data Breach at 23andMe Affects 6.9 Million Profiles, Company Says&#8221;</a></p><p><a href="https://www.nbcnews.com/news/us-news/23andme-user-data-targeting-ashkenazi-jews-leaked-online-rcna119324">&#8220;23andMe user data targeting Ashkenazi Jews leaked online&#8221;</a></p><p><a href="https://oag.ca.gov/news/press-releases/attorney-general-bonta-urgently-issues-consumer-alert-23andme-customers">&#8220;Attorney General Bonta Urgently Issues Consumer Alert for 23andMe Customers&#8221;</a></p><p><a href="https://www.congress.gov/bill/118th-congress/senate-bill/5433">U.S. Senate Bill S.5433: Genomic Data Protection Act</a></p><p>Ryan Schwarz</p><p><a href="https://www.milbank.org/publications/the-health-of-us-primary-care-2025-scorecard-report-the-cost-of-neglect/">&#8220;The Health of US Primary Care: 2025 Scorecard Report&#8212;The Cost of Neglect&#8221;</a></p><p><a href="https://www.commonwealthfund.org/publications/issue-briefs/2024/mar/finger-on-pulse-primary-care-us-nine-countries#:~:text=The%20U.S.%20spent%204.7%20percent,in%20other%20high%2Dincome%20countries">&#8220;Finger on the Pulse: The State of Primary Care in the U.S. and Nine Other Countries&#8221;</a></p><p><a href="https://www.chiamass.gov/massachusetts-health-insurance-survey">Massachusetts Health Insurance Survey</a></p><p><a href="https://link.springer.com/article/10.1007/s11606-022-07707-x">&#8220;Revisiting the Time Needed to Provide Adult Primary Care&#8221;</a></p><p><a href="https://hbr.org/2022/05/how-algorithms-could-improve-primary-care">&#8220;How Algorithms Could Improve Primary Care&#8221;</a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/36750508/">Ryan Schwarz: &#8220;Primary Care Sub-capitation in Medicaid: Improving Care Delivery in the Safety Net&#8221;</a></p><p><a href="https://www.mass.gov/info-details/masshealth-primary-care-sub-capitation-program-overview">MassHealth Primary Care Sub-Capitation: Program Overview</a></p><p><a href="https://journals.lww.com/ambulatorycaremanagement/fulltext/2005/10000/the_first_community_health_centers__a_model_of.6.aspx">&#8220;The first community health centers: a model of enduring value&#8221;</a></p><p><a href="https://www.commonwealthfund.org/publications/issue-briefs/2024/aug/community-health-centers-meeting-primary-care-needs-2024-FQHC-survey">&#8220;Community Health Centers&#8217; Progress and Challenges in Meeting Patients&#8217; Essential Primary Care Needs&#8221;</a></p><p>Match Day</p><p><a href="https://www.ama-assn.org/medical-students/preparing-residency/biggest-match-day-ever-here-s-what-2025-numbers-reveal">&#8220;Biggest Match Day ever: Here&#8217;s what the 2025 numbers reveal&#8221;</a></p><p><a href="https://medicine.yale.edu/news-article/yale-school-of-medicine-celebrates-exemplary-matches/">&#8220;Yale School of Medicine Celebrates Match Day&#8221;</a></p><p><a href="https://www.youtube.com/watch?v=ckbO6ykf2f8">Video: Match Day 2025: Winners &amp; Losers Edition</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item><item><title><![CDATA[Mark McClellan: An Economic Lens on Healthcare]]></title><description><![CDATA[Howie and Harlan are joined by Mark McLellan, a physician, economist, and longtime public servant, to discuss lessons learned from the COVID-19 response and the successes and failures of the healthcare payment innovations he helped to create. Harlan...]]></description><link>https://neverdelegateunderstanding.substack.com/p/mark-mcclellan-an-economic-lens-on-be2</link><guid isPermaLink="false">https://neverdelegateunderstanding.substack.com/p/mark-mcclellan-an-economic-lens-on-be2</guid><dc:creator><![CDATA[Harlan Krumholz]]></dc:creator><pubDate>Thu, 20 Mar 2025 13:07:00 GMT</pubDate><enclosure url="https://api.substack.com/feed/podcast/171298531/5c2497038b79559fffb6f6603bda0afd.mp3" length="0" type="audio/mpeg"/><content:encoded><![CDATA[<p>Howie and Harlan are joined by Mark McLellan, a physician, economist, and longtime public servant, to discuss lessons learned from the COVID-19 response and the successes and failures of the healthcare payment innovations he helped to create. Harlan reports on a wave of illness caused by slushy drinks; Howie considers the merits of accelerated training for doctors.</p><p>Links:</p><p>The Dangers of Slushies</p><p><a href="https://adc.bmj.com/content/early/2025/02/10/archdischild-2024-328109">&#8220;Glycerol intoxication syndrome in young children, following the consumption of slush ice drinks&#8221;</a></p><p><a href="https://www.instituteforgovernment.org.uk/explainer/sugar-tax">Institute for Government: Sugar tax</a></p><p>Mark McClellan</p><p><a href="https://hcp.hms.harvard.edu/people/alan-m-garber">Health economist Alan M. Garber, MD, PhD</a></p><p><a href="https://jamanetwork.com/journals/jama/fullarticle/388194">Mark McClellan: &#8220;Catheterization and Mortality in Elderly Patients With Acute Myocardial Infarction-Reply&#8221;</a></p><p><a href="https://www.aei.org/research-products/report/national-coronavirus-response-a-road-map-to-reopening/">Mark McClellan: &#8220;National Coronavirus Response: A Road Map to Reopening&#8221;</a></p><p><a href="https://www.healthsystemtracker.org/brief/covid-19-pandemic-related-excess-mortality-and-potential-years-of-life-lost-in-the-u-s-and-peer-countries/">&#8220;COVID-19 pandemic-related excess mortality and potential years of life lost in the U.S. and peer countries&#8221;</a></p><p><a href="https://hms.harvard.edu/news/medicare-should-put-its-dollars-value-says-mcclellan">&#8220;Medicare Should Put Its Dollars on Value, Says McClellan&#8221;</a></p><p><a href="https://www.hcinnovationgroup.com/policy-value-based-care/medicare-advantage/article/55268278/what-forced-cms-to-terminate-the-ma-value-base-insurance-design-model">&#8220;What Forced CMS to Terminate the MA Value-Based Insurance Design Model?&#8221;</a></p><p><a href="https://catalyst.nejm.org/doi/full/10.1056/CAT.21.0253">&#8220;How to Create Incentives for Improvement&#8221;</a></p><p>Accelerating Med School</p><p><a href="https://journals.lww.com/academicmedicine/abstract/2025/02000/outcomes_of_accelerated_3_year_md_graduates_at_nyu.20.aspx">&#8220;Outcomes of Accelerated 3-Year MD Graduates at NYU Grossman School of Medicine During Medical School and Early Residency&#8221;</a></p><p><a href="https://www.medscape.com/viewarticle/three-year-medical-school-has-benefits-ethicist-says-2024a1000onr?form=fpf">&#8220;Three-Year Medical School Has Benefits, Ethicist Says&#8221;</a></p><p><a href="https://som.yale.edu/programs/emba">Learn more about the MBA for Executives program at Yale SOM</a>.</p><p><a href="mailto:health.veritas@yale.edu">Email Howie and Harlan comments or questions.</a></p>]]></content:encoded></item></channel></rss>